3-(3,3-dimethyl-4H-isoquinolin-1-yl)-5-methoxy-7-methylquinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-(3,3-dimethyl-4H-isoquinolin-1-yl)-5-methoxy-7-methylquinoline
• 化学式: C₂₂H₂₂N₂O
• 分子量: 330.4
• InChiKey: BDINYNAJNXRQJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  34.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHOD FOR PRODUCING 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND PRODUCTION INTERMEDIATES OF SAME
  申请人：MITSUI CHEMICALS AGRO, INC.

  公开号：US20140228576A1

  公开（公告）日：2014-08-14

  Provided are an efficient method for producing 3,4-dihydroisoquinoline derivatives and useful production intermediates thereof. Provided is a method for producing 3,4-dihydroisoquinoline derivatives represented by general formula (1), comprising converting a compound represented by general formula (3) in the presence of acid after reacting with an aniline derivative, or converting a compound represented by general formula (3) by reacting with an aniline derivative in the presence of an acid.
• US9193706B2
  申请人：——

  公开号：US9193706B2

  公开（公告）日：2015-11-24
• US9499515B2
  申请人：——

  公开号：US9499515B2

  公开（公告）日：2016-11-22