1,10-dimethoxy-deca-2,8-diyne | 286859-72-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,10-dimethoxy-deca-2,8-diyne
• 英文别名: 1,10-Dimethoxy-deca-2,8-diin；1,10-Dimethoxydeca-2,8-diyne
• CAS: 286859-72-1
• 化学式: C₁₂H₁₈O₂
• 分子量: 194.274
• InChiKey: CKJWDIRCHXFVOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,10-dimethoxy-deca-2,8-diyne 在 镍 作用下， 生成 1,10-decanediol dimethyl ether
  参考文献：
  名称：

  Epsztein, Bulletin de la Societe Chimique de France, 1956, p. 158

  摘要：

  DOI：
• 作为产物：
  描述：

  氯甲基甲基醚 、 alkaline earth salt of/the/ methylsulfuric acid 在 氨 作用下， 生成 1,10-dimethoxy-deca-2,8-diyne
  参考文献：
  名称：

  Epsztein, Bulletin de la Societe Chimique de France, 1956, p. 158

  摘要：

  DOI：

文献信息

• Titanium-mediated intramolecular cyclization of tethered propargyl alcohol derivatives. Access to exocyclic bis-allenes and cyclobutene derivatives
  作者：Christophe Delas、Hirokazu Urabe、Fumie Sato

  DOI：10.1016/s0040-4039(01)00666-9

  日期：2001.6

  Treatment of tethered bis-propargyl alcohol derivatives with (η2-propene)Ti(O-i-Pr)2 afforded four- and five-membered rings bearing conjugated exocyclic bis-allenes. In the case of six- and seven-membered rings, bicyclic cyclobutenes were obtained in the same pot most likely via the intermediate bis-allenes.

  拴系双-炔丙基醇衍生物的处理（η 2 -丙烯）的Ti（O-我-Pr）2，得到四和五元环的轴承环外缀合双-丙二烯。在六元和七元环的情况下，双环环丁烯很可能是在同一锅中通过中间体双亚丙烯获得的。
• Marszak; Epsztein, Bulletin de la Societe Chimique de France, 1956, p. 160
  作者：Marszak、Epsztein

  DOI：——

  日期：——
• 10.1002/cctc.202400411
  作者：Bandyopadhyay, Uchchhal、Lancien, Antoine、Branquet, David、Lhoste, Jérôme、Comesse, Sébastien、Martel, Arnaud、Benhamou, Laure

  DOI：10.1002/cctc.202400411

  日期：——

  Knölker complexes have been recently used to perform the catalytic C1‐oxidation of unprotected sugars into sugar lactones. This oxidation method remained limited by the stability of the catalyst with the polyhydroxylated substrates. Our objective is now to overcome these limitations and extend this method to more challenging substrates such as disaccharides. We proposed in this paper two original designs of Knölker‐type complexes conceived to promote secondary H‐bond interactions with the OH groups of the substrates to stabilise the system and favour the transformation. In total, 8 novel pre‐catalysts were synthesised, fully characterised and applied in the anomeric oxidation of several sugar derivatives. Two of these new complexes proved to be more efficient than the Knölker complex for the oxidation of disaccharides. Moreover, a preliminary DFT study revealed the presence of H‐bonds interactions between the substrate and the oxygen atom on the ligand arm of the best complexes suggesting a beneficial role of this heteroatom on the catalytic efficiency.
• Epsztein, Bulletin de la Societe Chimique de France, 1956, p. 158
  作者：Epsztein

  DOI：——

  日期：——