(1E,4E)-1-[3-(hydroxymethyl)-5-methoxyphenyl]-5-(3-methoxy-5-methylphenyl)penta-1,4-dien-3-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (1E,4E)-1-[3-(hydroxymethyl)-5-methoxyphenyl]-5-(3-methoxy-5-methylphenyl)penta-1,4-dien-3-one
• 化学式: C₂₁H₂₂O₄
• 分子量: 338.4
• InChiKey: RRPJTKXZFTYDDK-YDFGWWAZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS
  申请人：STC. UNM

  公开号：US20160287531A1

  公开（公告）日：2016-10-06

  The present invention relates to method(s) of treating a subject afflicted with a skin disease or condition, the method comprising administering to the subject or patient in need a composition comprising a therapeutically effective amount of a substituted cis or trans-stilbene or a stilbene hybrid. A method of treating or reducing the likelihood of a skin disease or condition in a patient is an additional embodiment of the present invention. Preferred pharmaceutical compositions of the invention include nanoemulsions comprising a therapeutically effective amount of a substituted cis or trans-stilbene or stilbene hybrid and at least one antibiotic.
• US8841326B2
  申请人：——

  公开号：US8841326B2

  公开（公告）日：2014-09-23
• US9925153B2
  申请人：——

  公开号：US9925153B2

  公开（公告）日：2018-03-27