(2Z)-1-ethyl-2-[(Z)-3-(1-ethylquinolin-1-ium-4-yl)prop-2-enylidene]quinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: (2Z)-1-ethyl-2-[(Z)-3-(1-ethylquinolin-1-ium-4-yl)prop-2-enylidene]quinoline
• 化学式: C25H25N2+
• 分子量: 353.5
• InChiKey: ONKAXOHRKIYFDJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• REAGENT AND REAGENT KIT FOR ANALYSIS OF PRIMITIVE LEUKOCYTE
  申请人：Sysmex Corporation

  公开号：EP2166353A1

  公开（公告）日：2010-03-24

  The present invention provides a reagent for analysis of immature leukocytes comprising: a surfactant which can damage cell membranes of erythrocytes and mature leukocytes, a solubilizing agent which can shrink the damaged blood cells and a dye for staining nucleic acid, wherein the reagent has an osmotic pressure of not lower than 10 mOsm/kg and lower than 150 mOsm/kg.

  本发明提供了一种用于分析未成熟白细胞的试剂，包括 一种表面活性剂，可破坏红细胞和成熟白细胞的细胞膜、 可使受损血细胞缩小的增溶剂，以及 用于染色核酸的染料、 其中试剂的渗透压不低于 10 mOsm/kg，低于 150 mOsm/kg。
• Blood analyzer and method for determining existence and nonexistence of lymphoblasts in blood sample
  申请人：Sysmex Corporation

  公开号：EP2237019A2

  公开（公告）日：2010-10-06

  The invention provides a blood analyzer (1) comprising a blood sample supply section, a sample preparation section (22) for preparing an assay sample by mixing the blood sample with a nucleic acid-staining fluorescent dye, a light source for irradiating the assay sample, an optical detecting section (23) for receiving fluorescence emitted from the irradiated assay sample and a controller for performing operations comprising detecting a cell group comprising lymphoblasts on the basis of the fluorescence received by the optical detecting section (23), and outputting an information on an appearance of the lymphoblasts in the blood sample, as well as a method for determining the existence and nonexistence of lymphoblasts in a blood sample.

  本发明提供了一种血液分析仪（1），包括一个血液样本供应部分、一个用于通过将血液样本与核酸染色荧光染料混合来制备检测样本的样本制备部分（22）、一个用于照射检测样本的光源、光学检测部分（23），用于接收从照射后的检测样本发出的荧光；控制器，用于执行包括根据光学检测部分（23）接收到的荧光检测包括淋巴母细胞在内的细胞群、输出血液样本中淋巴母细胞的外观信息等操作，以及确定血液样本中是否存在淋巴母细胞的方法。
• Blood analyzer, method and computer program for determining existence and nonexistence of lymphoblasts in blood sample
  申请人：Sysmex Corporation

  公开号：EP2237019B1

  公开（公告）日：2016-04-27
• REAGENT AND REAGENT KIT FOR ANALYSIS OF IMMATURE LEUKOCYTE
  申请人：Kataoka Yukiko

  公开号：US20100184061A1

  公开（公告）日：2010-07-22

  The present invention provides a reagent for analysis of immature leukocytes comprising: a surfactant which can damage cell membranes of erythrocytes and mature leukocytes, a solubilizing agent which can shrink the damaged blood cells and a dye for staining nucleic acid, wherein the reagent has an osmotic pressure of not lower than 10 mOsm/kg and lower than 150 mOsm/kg.
• BLOOD ANALYZER AND METHOD FOR DETERMINING EXISTENCE AND NONEXISTENCE OF LYMPHOBLASTS IN BLOOD SAMPLE
  申请人：KATAOKA Yukiko

  公开号：US20100248247A1

  公开（公告）日：2010-09-30

  The invention provides a blood analyzer comprising a blood sample supply section, a sample preparation section for preparing an assay sample by mixing the blood sample with a nucleic acid-staining fluorescent dye, a light source for irradiating the assay sample, an optical detecting section for receiving fluorescence emitted from the irradiated assay sample and a controller for performing operations comprising detecting a cell group comprising lymphoblasts on the basis of the fluorescence received by the optical detecting section, and outputting an information on an appearance of the lymphoblasts in the blood sample, as well as a method for determining the existence and nonexistence of lymphoblasts in a blood sample.