葡萄糖酸铵 | 19222-41-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 葡萄糖酸铵
• 英文名称: ammonium D-gluconate
• 英文别名: Gluconic acid, monoammonium salt；azanium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
• CAS: 19222-41-4
• 化学式: C₆H₁₂O₇*H₃N
• 分子量: 213.188
• InChiKey: XLCNHLXQKYRGKZ-JJKGCWMISA-N

物化性质

• 熔点：
  154 °C (decomp)
• 物理描述：
  Ammonium gluconate is a white solid with a weak odor of ammonia. Sinks and mixes with water. (USCG, 1999)
• 颜色/状态：
  NEEDLES
• 溶解度：
  IN WATER: 31.6 G/100 ML @ 25 °C; SLIGHTLY SOL IN ALCOHOL; PRACTICALLY INSOL IN MOST ORGANIC SOLVENTS
• 密度：
  greater than 1 at 68 °F (USCG, 1999)
• 稳定性/保质期：
  TURNS YELLOW ON EXPOSURE TO LIGHT
• 旋光度：
  SPECIFIC OPTICAL ROTATION: +11.6 DEG IN WATER

计算性质

• 辛醇/水分配系数(LogP)：
  -3.33
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  139
• 氢给体数：
  7
• 氢受体数：
  8

安全信息

• 海关编码：
  2918160000

反应信息

• 作为反应物：
  描述：

  氢碘酸 、 葡萄糖酸铵 、 alkaline earth salt of/the/ methylsulfuric acid 生成 己酸
  参考文献：
  名称：

  Th.Schmidt,O., Justus Liebigs Annalen der Chemie, 1929, vol. 476, p. 269

  摘要：

  DOI：
• 作为产物：
  描述：

  葡萄糖 在 mercury(II) diacetate 、 氨 作用下， 生成 葡萄糖酸铵
  参考文献：
  名称：

  Ingvaldsen; Bauman, Journal of Biological Chemistry, 1920, vol. 41, p. 147

  摘要：

  DOI：

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• [EN] NOVEL ANTIBACTERIAL HYDROGELS<br/>[FR] NOUVEAUX HYDROGELS ANTIBACTÉRIENS
  申请人：NEWSOUTH INNOVATIONS PTY LTD

  公开号：WO2021253087A1

  公开（公告）日：2021-12-23

  The present invention relates to compounds of Formula I which form hydrogels upon mixing with water, and to fibers which form from the compounds. The hydrogels and fibers are antibacterial and not toxic towards mammalian cells. Such compounds, hydrogels, and fibers are useful, for example, in the treatment of surfaces such as in dermal or internal wounds as a barrier layer, or any article which may require disinfection. (I)

  本发明涉及一种化合物，其化学式为I，在与水混合后形成水凝胶，并且形成自该化合物的纤维。这些水凝胶和纤维具有抗菌性，并且对哺乳动物细胞不具有毒性。这些化合物、水凝胶和纤维可用于例如在治疗表面如皮肤或内部伤口时作为屏障层，或者任何可能需要消毒的物品中。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• Cosmetic compositions comprising a cation, a drawing polymer and a thickener, and cosmetic treatment processes
  申请人：Fack Geraldine

  公开号：US20050175569A1

  公开（公告）日：2005-08-11

  The present disclosure relates to cosmetic compositions comprising, in a cosmetically acceptable medium, at least one cationic surfactant, at least one drawing polymer, and at least one non-cellulose-based thickening polymer, and to cosmetic processes for treating keratin materials, such as the hair. These compositions have an improved styling effect.

  本公开涉及化妆品组合物，包括至少一种阳离子表面活性剂、至少一种拉伸聚合物和至少一种非纤维素基增稠聚合物，以及用于处理角蛋白材料（例如头发）的化妆品过程，这些组合物具有改善的造型效果，均在化妆品可接受的介质中。
• Systems and Methods for Treating Ear Disorders and Formulations Therefor
  申请人：YAACOBI Yoseph

  公开号：US20160022666A1

  公开（公告）日：2016-01-28

  An apparatus for insertion in an ear is provided and includes a drug delivery device for insertion into an external auditory canal, wherein the drug delivery device contains one or more pharmaceutically active agents that can be released from the drug delivery device into the external auditory canal and onto the tympanic membrane to treat ear disorders. In more particular instances, the drug delivery device can conform to the profile of the external auditory canal. Formulations of agents for the drug delivery device are also provided.

  提供一种用于插入耳朵的装置，其中包括一个药物输送装置，可插入外耳道，该药物输送装置含有一种或多种药用活性剂，可从药物输送装置中释放到外耳道和鼓膜上，以治疗耳部疾病。在更具体的情况下，药物输送装置可以符合外耳道的轮廓。还提供了药物输送装置的药剂配方。