Ethanone, 1-(1,2,3,4,5,6,7,8-octahydro-2,3,5,5-tetramethyl-2-naphthalenyl)- | 54464-59-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Ethanone, 1-(1,2,3,4,5,6,7,8-octahydro-2,3,5,5-tetramethyl-2-naphthalenyl)-
• 英文别名: 1-(2,3,5,5-tetramethyl-1,3,4,6,7,8-hexahydronaphthalen-2-yl)ethanone
• CAS: 54464-59-4
• 化学式: C₁₆H₂₆O
• 分子量: 234.38
• InChiKey: LCZYWDBISQLZSE-UHFFFAOYSA-N

物化性质

• 沸点：
  312.2±31.0 °C(Predicted)
• 密度：
  0.95±0.1 g/cm3(Predicted)
• LogP：
  5.001 (est)
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] HISTONE DEACETYLASE INHIBITORS<br/>[FR] INHIBITEURS DE L'HISTONE DÉSACÉTYLASE
  申请人：MERCK & CO INC

  公开号：WO2006017216A1

  公开（公告）日：2006-02-16

  This invention relates to hydroxamic acid derivatives having a urea linkage, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.

  这项发明涉及具有脲键的羟羟基脂肪酸衍生物，这些衍生物是组蛋白去乙酰化酶（HDAC）的抑制剂，可用于预防和/或治疗细胞增殖性疾病，例如癌症、自身免疫、过敏和炎症性疾病，中枢神经系统（CNS）疾病如神经退行性疾病，以及预防和/或治疗再狭窄。
• Hair growth composition
  申请人：RIKEN

  公开号：US10543227B2

  公开（公告）日：2020-01-28

  The invention of this application relates to a composition for growing hairs comprising, as an active ingredient, thiosulfuric acid or a salt thereof that has hair growing effects and has no side effects.

  本申请的发明涉及一种生发组合物，其活性成分包括硫代硫酸或其盐类，具有生发效果且无副作用。
• Method of resolving defined known or suspected allergens in a complex mixture of perfume ingredients, and compositions
  申请人：GIVAUDAN SA

  公开号：US11002716B2

  公开（公告）日：2021-05-11

  Analytical methods that can be employed to reliably separate known or suspected allergens in a complex mixture of fragrance ingredients are described.

  描述了可用于可靠分离香料成分复杂混合物中已知或可疑过敏原的分析方法。
• Perfume mixtures with increased odor intensity
  申请人：——

  公开号：US20020192174A1

  公开（公告）日：2002-12-19

  The present invention relates to perfume mixtures, their use in hair care products and hair care products containing these perfume mixtures. The odor of the perfume mixtures according to the present invention is particularly strongly perceived during or after hair-drying.

  本发明涉及香水混合物、它们在护发产品中的用途以及含有这些香水混合物的护发产品。根据本发明，香水混合物的气味在吹干头发时或吹干头发后特别强烈。
• RIECHSTOFFMISCHUNGEN MIT GESTEIGERTER GERUCHSTÄRKE
  申请人：Symrise GmbH & Co. KG

  公开号：EP1385470B1

  公开（公告）日：2007-08-08