(2E)-3-methyl-2-[(1-methylquinolin-1-ium-4-yl)methylidene]-1,3-benzothiazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: (2E)-3-methyl-2-[(1-methylquinolin-1-ium-4-yl)methylidene]-1,3-benzothiazole
• 化学式: C19H17N2S+
• 分子量: 305.4
• InChiKey: XRXJDLHDDHBJOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  32.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Primer, primer set, and nucleic acid amplification method and mutation detection method using the same
  申请人：Hayashizaki Yoshihide

  公开号：US20080227104A1

  公开（公告）日：2008-09-18

  The present invention provides a primer that effectively can detect, for example, the double helix structure of a nucleic acid. The primer is a labeled nucleic acid containing at least one structure represented by the following formula (16), where B is an atomic group having a nucleobase skeleton, E is an atomic group having a deoxyribose skeleton, a ribose skeleton, or a structure derived from either one of them, or an atomic group having a peptide structure or a peptoid structure, and Z 11 and Z 12 are each an atomic group that exhibits fluorescence and are identical to or different from each other.

  本发明提供了一种引物，可以有效地检测核酸的双螺旋结构，例如。该引物是一种带标记的核酸，其中至少包含下式（16）所表示的一个结构，其中B是具有核苷酸骨架的原子团，E是具有脱氧核糖骨架，核糖骨架或从它们中的任何一个派生的结构，或具有肽结构或肽酰结构的原子团，而Z11和Z12是各自表现出荧光的原子团，它们相同或不同。
• Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes
  申请人：Ignatyev Nikolai (Mykola)

  公开号：US20080275224A1

  公开（公告）日：2008-11-06

  The present invention relates to dyes of the general formula CAT + Y − (I), where Y − is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT + is a cation selected from the group of the azine, xanthene, polymethine, styryl, azo, tetrazolium, pyrylium, benzopyrylium, thiopyrylium, benzothiopyrylium, thiazine, oxazine, triarylmethane, diarylmethane, methine, acridine, quinoline, isoquinoline or quaternary azafluorenone dyes, for colouring plastics and plastic fibres, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp ink, for colouring leather and paper, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry.

  本发明涉及一般公式CAT+Y-（I）的染料，其中Y-是从氰硼酸盐、氟烷基磷酸盐、氟烷基硼酸盐或咪唑盐组中选择的阴离子，CAT+是从吖嗪、黄色素、聚甲烯、苯乙烯、偶氮、四唑、吡啶杂环、苯并吡喃杂环、硫吡喃杂环、苯并硫吡喃杂环、噻吩、噁吩、三芳基甲烷、二芳基甲烷、甲烯、花菁、喹啉、异喹啉或季铵氮杂花菁染料组中选择的阳离子，用于染色塑料和塑料纤维，用于制备凹版印刷油墨，作为圆珠笔浆料、邮票墨水，用于染色皮革和纸张，用于数据采集系统、复印、油墨微滤器、光电镀、激光技术和照相产业。
• CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES
  申请人：IGNATYEV Nikolai (Mykola)

  公开号：US20110190480A1

  公开（公告）日：2011-08-04

  The present invention relates to dyes of the general formula CAT + Y − (I), where Y − is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT + is a cation selected from the group of the azine, xanthene, polymethine, styryl, azo, tetrazolium, pyrylium, benzopyrylium, thiopyrylium, benzothiopyrylium, thiazine, oxazine, triarylmethane, diarylmethane, methine, acridine, quinoline, isoquinoline or quaternary azafluorenone dyes, for colouring plastics and plastic fibres, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp ink, for colouring leather and paper, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry.

  本发明涉及一般式CAT+Y−（I）的染料，其中Y−是从氰硼酸盐、氟烷基磷酸盐、氟烷基硼酸盐或咪唑盐群中选择的阴离子，CAT+是从偶氮、黄色素、聚甲烯、苯乙烯、偶氮、四唑、吡啶、苯并吡喃、硫吡喃、苯并硫吡喃、噻吩、噁唑、三芳基甲烷、二芳基甲烷、甲烷、吖啶、喹啉、异喹啉或季铵氮芴酮染料群中选择的阳离子，用于着色塑料和塑料纤维，制备柔性版印刷油墨，作为圆珠笔膏、邮票墨水，用于着色皮革和纸张，用于数据采集系统，复印术，墨水微滤器，光电镀技术，激光技术和光学工业。
• Dyes and Labeled Molecules
  申请人：AlleLogic Biosciences Corporation

  公开号：US20140106349A1

  公开（公告）日：2014-04-17

  Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example.

  提供了二聚和三聚核酸染料，以及相关系统和方法。这样的染料可以形成类似发夹的结构，使其通过按需释放机制染色核酸。例如，这样的染料在没有核酸存在时具有低背景荧光，在与核酸结合后具有高荧光，例如。本文提供的染料可以在各种应用中有用，例如在实时PCR中用于DNA定量。
• Réactif de coloration pour la détermination de cellules sanguines
  申请人：ABX

  公开号：EP0856735A1

  公开（公告）日：1998-08-05

  L'invention concerne un réactif de coloration pour la détermination de cellules sanguines, en particulier de réticulocytes, qui comprend un colorant propre à marquer les cellules après incubation ainsi qu'un additif propre à favoriser la pénétration du colorant dans les cellules, cet additif étant choisi parmi un composé ionophore, un détergent et leur mélange.

  本发明涉及一种用于测定血细胞，特别是网状细胞的染色试剂，它包括一种能在孵育后标记细胞的染料和一种能促进染料渗透到细胞中的添加剂，这种添加剂可从离子型化合物、洗涤剂及其混合物中选择。