1-Isopropyl-s-triazolo<4,3-a>chinolin | 41493-72-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-Isopropyl-s-triazolo<4,3-a>chinolin
• 英文别名: 1-isopropyl-[1,2,4]triazolo[4,3-a]quinoline；1-Isopropyl-[1,2,4]triazolo[4,3-a]chinolin；1-Isopropyl[1,2,4]triazolo[4,3-a]quinoline；1-propan-2-yl-[1,2,4]triazolo[4,3-a]quinoline
• CAS: 41493-72-5
• 化学式: C₁₃H₁₃N₃
• 分子量: 211.266
• InChiKey: VJXRNWAXFMJNEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  30.2
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-肼喹啉 、 异丁酸 生成 1-Isopropyl-s-triazolo<4,3-a>chinolin
  参考文献：
  名称：

  The Synthesis of Polyazaindenes and Related Compounds

  摘要：

  DOI：

  10.1021/jo01092a023

文献信息

• Stabilized photographic emulsions
  申请人：EASTMAN KODAK CO

  公开号：US02865749A1

  公开（公告）日：1958-12-23
• Heterocyclic Aromatic Compounds Useful As Growth Hormone Secretagogues
  申请人：Yu Guixue

  公开号：US20090324625A1

  公开（公告）日：2009-12-31

  Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R 1 , R 1 ′, R 2 , R 3 , R 4 , Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
• HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES
  申请人：Yu Guixue

  公开号：US20120252799A1

  公开（公告）日：2012-10-04

  Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R 1 , R 1 ′, R 2 , R 3 , R 4 , Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
• US7166596B2
  申请人：——

  公开号：US7166596B2

  公开（公告）日：2007-01-23
• US7592354B2
  申请人：——

  公开号：US7592354B2

  公开（公告）日：2009-09-22