triethylene glycol monopropionate | 52709-48-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: triethylene glycol monopropionate
• 英文别名: Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-, propanoate；2-[2-(2-hydroxyethoxy)ethoxy]ethyl propanoate
• CAS: 52709-48-5
• 化学式: C₉H₁₈O₅
• 分子量: 206.239
• InChiKey: CLDXGLBKECXSBG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• PEPTIDE OLIGONUCLEOTIDE CONJUGATES
  申请人：Hanson Gunnar J.

  公开号：US20120289457A1

  公开（公告）日：2012-11-15

  Oligonucleotide analogues conjugated to carrier peptides are provided. The disclosed compounds are useful for the treatment of various diseases, for example diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

  提供了与载体肽共轭的寡核苷酸类似物。所公开的化合物可用于治疗各种疾病，例如抑制蛋白质表达或校正异常的mRNA剪接产物可产生有益的治疗效果的疾病。
• Tobacco filters and method of producing the same
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP0634113A2

  公开（公告）日：1995-01-18

  A filter rod is produced by adding a water-soluble polymer in the form of an aqueous solution or dispersion, or in a particulate form, to a tow of cellulose ester fiber, with the amount of any water used being controlled within 25 parts by weight relative to 100 parts by weight of the tow, and wrapping the treated tow in wrapping paper. The water contained in the filter rod is removed or the particulate water-soluble polymer is melted by heating to bond the fiber to provide a tobacco filter. The proportion of the water soluble polymer is 0.5 to 30 parts by weight to 100 parts by weight of the tow. To reduce the amount of water relative to the tow, a hot-melt adhesive water-soluble polymer may be employed. As the amount of water added to the tow is thus decreased, the tow can be smoothly wrapped up even at a high speed so that filter productivity is improved. This tobacco filter is highly wet-disintegratable and, hence, contributes to mitigation of the environmental pollution.

  在纤维素酯纤维丝束中加入水溶液或分散体形式的水溶性聚合物，或颗粒形式的水溶性聚合物，生产滤棒，相对于 100 重量份的纤维素酯纤维丝束，用水量控制在 25 重量份以内，然后用包装纸包裹处理过的纤维素酯纤维丝束。滤棒中的水被除去，或者颗粒状的水溶性聚合物被加热融化，使纤维粘合在一起，形成烟草过滤嘴。水溶性聚合物的比例为 0.5 至 30（按重量计）比 100（按重量计）丝束。为了减少相对于丝束的水量，可以使用热熔粘合剂水溶性聚合物。这样，添加到丝束中的水量就减少了，即使在高速运转时，丝束也能顺利地缠绕起来，从而提高过滤效率。这种烟草过滤器具有很强的湿分解性，因此有助于减轻环境污染。
• Tobacco filters and production process thereof
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP0766929A2

  公开（公告）日：1997-04-09

  Water disintegratability of a tobacco filter is improved by incorporating a super absorbent resin into a tobacco smoke filter medium in a tobacco filter comprising a main constitutive element of the tobacco smoke filter medium, and a water-soluble polymer as a binder for shaping the constitutive element. The constitutive element includes particulate or fibrous cellulose and cellulose esters (e.g. cellulose acetate). The water-absorption ratio of the super absorbent resin is about 10 to 1,000 times, and the amount of the resin is about 0.05 to 50 parts by weight relative to 100 parts by weight of the main constitutive element of the tobacco smoke filter medium.

  通过在烟草滤嘴中的烟草烟雾过滤介质中加入超吸水性树脂，提高了烟草滤嘴的脱水性能，烟草滤嘴的烟雾过滤介质由烟草烟雾过滤介质的主要构成元素和水溶性聚合物组成，水溶性聚合物是塑造构成元素的粘合剂。构成元素包括颗粒状或纤维状纤维素和纤维素酯（如醋酸纤维素）。超吸水性树脂的吸水率约为 10 至 1 000 倍，相对于 100 重量份的烟草烟雾过滤介质主要构成元素，树脂的用量约为 0.05 至 50 重量份。
• Process for preventing consolidation of P-Dichlorobenzene
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0520510B1

  公开（公告）日：1995-09-27
• COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS
  申请人：ModernaTX, Inc.

  公开号：US20180028664A1

  公开（公告）日：2018-02-01

  This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.