Monoamine Triethylene Glycol | 131324-11-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Monoamine Triethylene Glycol
• 英文别名: Azane;2-[2-(2-hydroxyethoxy)ethoxy]ethanol
• CAS: 131324-11-3
• 化学式: C₆H₁₄O₄*H₃N
• 分子量: 167.205
• InChiKey: AGAMSSXYOIENHK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.83
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  59.9
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  三苯基膦 在 碳酸氢钠 作用下， 以91%的产率得到Monoamine Triethylene Glycol
  参考文献：
  名称：

  COMPACT AND HOMOGENEOUS QUANTUM DOTS AND METHODS OF MAKING THE SAME

  摘要：

  本公开提供了量子点及其制备方法，其中包括一个基本均匀的单体纳米晶体种群，大小非常小，直径约为7纳米到12纳米。该方法包括将涂有弱结合配体或离子的纳米晶体与聚合物在溶液中混合，并在温度大于约100°C的条件下孵育，从而形成具有基本均匀的单体纳米晶体种群的量子点。这些量子点可以进一步与生物亲和分子结合，使得紧凑的、生物功能的量子点可以广泛应用于研究拥挤的大分子环境。

  公开号：

  US20200025772A1

文献信息

• Fast-acting insulin formulation comprising a substituted anionic compound and a polyanionic compound
  申请人：ADOCIA

  公开号：US20160015814A1

  公开（公告）日：2016-01-21

  A composition, in aqueous solution, comprising insulin in hexameric form, at least one substituted anionic compound and at least one polyanionic compound, said substituted anionic compound consisting of a discrete number n of between 1 and 8 of identical or different saccharide units, linked via identical or different glycoside bonds, said saccharide unit or one of said saccharide units being in open, oxidized or reduced form, said compound comprising salifiable carboxyl groups and said substituted anionic compound bearing on its reductive chain end at least one radical AA resulting from an aromatic amino acid comprising a phenyl or an indole, which may or may not be substituted, or an aromatic amino acid derivative comprising a phenyl or an indole, which may or may not be substituted.

  一种水溶液中的组合物，包括六聚体形式的胰岛素、至少一种取代的阴离子化合物和至少一种多阴离子化合物，所述取代的阴离子化合物由1到8个相同或不同的糖分子单元组成，通过相同或不同的糖苷键连接，其中的糖分子单元或其中的一个处于开放、氧化或还原形式，该化合物包含可盐化的羧基，且该取代的阴离子化合物在其还原链端具有至少一个来自含有苯基或吲哚基（可能被取代或未被取代）的芳香氨基酸或含有苯基或吲哚基（可能被取代或未被取代）的芳香氨基酸衍生物的AA基团。
• HETEROCYCLIC COMPOUND
  申请人：Fimecs, Inc.

  公开号：EP4006037A1

  公开（公告）日：2022-06-01

  It is to provide a novel heterocyclic compound which has the effect of inducing degradation of interleukin-1 receptor-associated kinase-M (IRAK-M) protein and is expected to be useful for the prevention/treatment of cancer, fibrosis, infectious diseases, etc. The present invention provides a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof.

  本发明旨在提供一种新的杂环化合物，具有诱导白细胞介素-1受体相关激酶M（IRAK-M）蛋白降解的效果，并有望用于预防/治疗癌症、纤维化、传染病等。本发明提供一种由以下公式（I）表示的化合物或其药学上可接受的盐。
• ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE
  申请人：Burckhardt Urs

  公开号：US20100101455A1

  公开（公告）日：2010-04-29

  The present invention relates in a first consideration to aldimines of formula (I). Said aldimines are particularly suitable as latent hardeners in curable compositions, particularly compositions comprising one or two-component isocyanate groups. Due to the presence of the reactive group, they can be converted to compounds of the formulas (X) and (XII) comprising aldimine groups, implementing a further consideration of the present invention. The aldimines, or the compounds comprising aldimine groups, can be used primarily in adhesive and sealant materials, but also in coatings, and can be produced easily from readily available source materials, and have good thermal stability. The tertiary amino group thereof has a surprisingly low alkalinity and can in some cases have a catalytic effect in chemical reaction systems.

  本发明涉及公式(I)的醛胺，首先考虑这些醛胺作为可固化组合物的潜在固化剂，特别是含有一种或两种异氰酸基团的组合物。由于具有反应性基团，它们可以转化为公式(X)和(XII)的化合物，包括醛胺基团，这是本发明的进一步考虑。这些醛胺或含有醛胺基团的化合物主要可用于粘合剂和密封材料，也可用于涂料，并且可以从易得的原料中轻松制备，并具有良好的热稳定性。其中的三级氨基具有惊人的低碱度，在某些情况下可以在化学反应系统中具有催化作用。
• ALDIMINE AND COMPOSITION CONTAINING ALDIMINE
  申请人：BURCKHARDT Urs

  公开号：US20110253309A1

  公开（公告）日：2011-10-20

  Aldimines of Formula (I), which can be used as latent curing agents in curing compositions, for example, in moisture-curing polyurethane compositions that have isocyanate groups. The aldimines are compounds that can be liquid at room temperature, can have a hardly noticeable aldehyde odor before, during and after hydrolysis, and can have a long shelf life. An aldehyde in polyurethane compositions that is released during hydrolysis has only a slight softening effect and can exhibit very little tendency to migrate or exude.

  式(I)的醛缩胺可以用作固化组合物中的潜在固化剂，例如在具有异氰酸酯基团的湿气固化聚氨酯组合物中。这些醛缩胺化合物可以在室温下为液体，水解前、期间和后几乎没有醛类气味，并且可以具有很长的货架寿命。在水解期间释放的聚氨酯组合物中的醛仅具有轻微的软化效果，并且可以表现出极少的迁移或渗出倾向。
• Novel bismaleimide derivatives
  申请人：TEXACO DEVELOPMENT CORPORATION

  公开号：EP0318162A2

  公开（公告）日：1989-05-31

  Novel bismaleimides of the formula wherein n=1,2 or 3 are formed in two steps by reacting a diamine and maleic anhydride to form a bismaleic acid which is reacted with acetic anhydride in the presence of acetone to form the bismaleimide. This can then be further reacted with a high molecular weight polyoxyalkyleneamine resulting in a novel bismaleimide derivative of a higher molecular weight polyoxyalkyleneamine, which derivative has the general formula: wherein R¹ and R² are independently alkyl or hydrogen, x, y and z depend on the amine used, n is 1, 2 or 3 and m is predominantly 1.

  新型双马来酰亚胺的化学式为 其中 n=1、2 或 3 分两步形成，先将二胺和马来酸酐反应生成双马来酸，双马来酸在丙酮存在下与乙酸酐反应生成双马来酰亚胺。然后再与高分子量的聚氧亚烷基胺反应，得到一种新型的高分子量聚氧亚烷基胺双马来酰亚胺衍生物，该衍生物的通式为 其中 R¹ 和 R² 独立地为烷基或氢，x、y 和 z 取决于所使用的胺，n 为 1、2 或 3，m 主要为 1。