p-Bromo-(1-methoxyethoxy)benzene | 157057-22-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: p-Bromo-(1-methoxyethoxy)benzene
• 英文别名: 1-bromo-4-(1-methoxyethoxy)benzene
• CAS: 157057-22-2
• 化学式: C₉H₁₁BrO₂
• 分子量: 231.09
• InChiKey: ULJSKEYPVFJNFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  二甲基砜 、 sodium;hydride 、 p-Bromo-(1-methoxyethoxy)benzene 、 四氢呋喃 以 二甲基亚砜 为溶剂， 反应 0.5h， 以Then to this mixture, a solution of methyl 3-phenylpropionate (36.6 g, 0.22 mole) obtained in above (1) in tetrahydrofuran (110 ml)的产率得到3-苯丙酸甲酯
  参考文献：
  名称：

  Resist material and pattern formation process

  摘要：

  一种电阻抗成分，包括(a)至少具有如下重复单元的聚合物：##STR1## (b) 光酸发生剂和(c) 溶剂，具有高光敏度，优异的耐热性，对基板的粘附性，并适用于高分辨率的图案形成。

  公开号：

  US05468589A1
• 作为产物：
  描述：

  4-溴苯酚 、 乙烯基甲醚 在 crude oil 作用下， 以to afford 20.8 g of p-bromo-(1-methoxyethoxy)benzene as a pale yellow oil的产率得到p-Bromo-(1-methoxyethoxy)benzene
  参考文献：
  名称：

  Resist material and pattern formation process

  摘要：

  一种电阻抗成分，包括(a)至少具有如下重复单元的聚合物：##STR1## (b) 光酸发生剂和(c) 溶剂，具有高光敏度，优异的耐热性，对基板的粘附性，并适用于高分辨率的图案形成。

  公开号：

  US05468589A1

文献信息

• ALLOSTERIC ENHANCERS OF THE A1 ADENOSINE RECEPTOR
  申请人：Baraldi Pier Giovanni

  公开号：US20090281145A1

  公开（公告）日：2009-11-12

  The present invention provides compounds of formula (I) wherein W, R 1 , R 5 and R 6 have a meaning as defined herein in the specification. The compounds of formula (I) are allosteric enhancers of the A 1 adenosine receptor and, thus, may be employed for the treatment of conditions mediated by the A 1 adenosine receptor. Accordingly, the compounds of formula (I) may be employed for treatment of pain, in particular, chronic pain such as neuropathic pain, and inflammatory pain, cardiac disease or disorder such as cardiac disarrhythmias, e.g., peroxysmal supraventricular tachycardia, angina, myocardial infarction and stroke, neurological disease or injury, sleep disorders, epilepsy and depression.

  本发明提供了式(I)的化合物 其中W，R1，R5和R6在本说明书中定义的含义。式(I)的化合物是A1腺苷受体的变构增强剂，因此可用于治疗由A1腺苷受体介导的疾病。因此，式(I)的化合物可用于治疗疼痛，特别是神经病性疼痛、炎症性疼痛、心脏疾病或紊乱，如心律失常，例如阵发性室上性心动过速，心绞痛，心肌梗死和中风，神经疾病或损伤，睡眠障碍，癫痫和抑郁症的治疗。
• Resist material and pattern formation process
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：US05468589A1

  公开（公告）日：1995-11-21

  A resist composition comprising (a) a polymer having at least repeating units of the formulae: ##STR1## (b) a photoacid generator and (c) a solvent, has high sensitivity to light, excellent heat resistance, adhesiveness to a substrate and suitable for pattern formation with high resolution.

  一种电阻抗成分，包括(a)至少具有如下重复单元的聚合物：##STR1## (b) 光酸发生剂和(c) 溶剂，具有高光敏度，优异的耐热性，对基板的粘附性，并适用于高分辨率的图案形成。
• Allosteric Enhancers of th A1 Adenosine Receptor
  申请人：Baraldi Pier Giovanni

  公开号：US20120108636A1

  公开（公告）日：2012-05-03

  The present invention provides compounds of formula (I) wherein W, R 1 , R 5 and R 6 have a meaning as defined herein in the specification. The compounds of formula (I) are allosteric enhancers of the A 1 adenosine receptor and, thus, may be employed for the treatment of conditions mediated by the A 1 adenosine receptor. Accordingly, the compounds of formula (I) may be employed for treatment of pain, in particular, chronic pain such as neuropathic pain, and inflammatory pain, cardiac disease or disorder such as cardiac disarrhythmias, e.g., peroxysmal supraventricular tachycardia, angina, myocardial infarction and stroke, neurological disease or injury, sleep disorders, epilepsy and depression.

  本发明提供了式（I）化合物，其中W、R1、R5和R6的含义如本规范中所定义。式（I）化合物是A1腺苷受体的别构增强剂，因此可以用于治疗由A1腺苷受体介导的疾病。因此，式（I）化合物可以用于治疗疼痛，特别是神经病理性疼痛和炎症性疼痛，心脏疾病或疾病，如心脏心律失常，例如阵发性室上性心动过速，心绞痛，心肌梗塞和中风，神经系统疾病或损伤，睡眠障碍，癫痫和抑郁症。
• Fine pattern forming material and pattern formation process
  申请人：WAKO PURE CHEMICAL INDUSTRIES LTD

  公开号：EP0588544A2

  公开（公告）日：1994-03-23

  A resist material comprising (a) a copolymer having as a functional group wherein R2 and R3 are, e.g. C1-6 alkyl, and R4 is, e.g. C1-10 alkyl, (b) a compound which generates an acid when exposed to electron beams, and (c) a solvent, is suitable for forming a chemical-amplified positive-working fine pattern with high resolution and good shape.

  一种抗蚀剂材料，包括 (a) 具有以下官能团的共聚物 其中 R2 和 R3 为 C1-6 烷基，R4 为 C1-10 烷基；(b) 一种在电子束照射下会产生酸的化合物；(c) 一种溶剂。
• [EN] ALLOSTERIC ENHANCERS OF THE A1 ADENOSINE RECEPTOR<br/>[FR] STIMULATEURS ALLOSTÉRIQUES DU RÉCEPTEUR A1 À L'ADÉNOSINE
  申请人：KING PHARMACEUTICALS RES & DEV

  公开号：WO2009137782A2

  公开（公告）日：2009-11-12

  The present invention provides compounds of formula (I) wherein W, R1, R5 and R6 have a meaning as defined herein in the specification. The compounds of formula (I) are allosteric enhancers of the A1 adenosine receptor and, thus, may be employed for the treatment of conditions mediated by the A1 adenosine receptor. Accordingly, the compounds of formula (I) may be employed for treatment of pain, in particular, chronic pain such as neuropathic pain, and inflammatory pain, cardiac disease or disorder such as cardiac disarrhythmias, e.g., peroxysmal supraventricular tachycardia, angina, myocardial infarction and stroke, neurological disease or injury, sleep disorders, epilepsy and depression.