Acetic acid 5-acetoxy-2-acetyl-4-(3-methyl-but-2-enyl)-phenyl ester | 35817-07-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Acetic acid 5-acetoxy-2-acetyl-4-(3-methyl-but-2-enyl)-phenyl ester
• 英文别名: [4-Acetyl-5-acetyloxy-2-(3-methylbut-2-enyl)phenyl] acetate
• CAS: 35817-07-3
• 化学式: C₁₇H₂₀O₅
• 分子量: 304.343
• InChiKey: LZVPORFYGQCSON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  69.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Acetic acid 5-acetoxy-2-acetyl-4-(3-methyl-but-2-enyl)-phenyl ester 在 水 、 sodium acetate 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以98%的产率得到1-[2,4-二羟基-5-(3-甲基丁-2-烯基)苯基]乙酮
  参考文献：
  名称：

  NaOAc-Mediated Selective Deprotection of Aromatic Acetates and Its Application in the Synthesis of Natural Products

  摘要：

  We have developed an efficient method to deacetylate the aromatic acetates using NaOAc in excellent yields and demonstrated the application of the procedure in the synthesis of natural products.

  DOI：

  10.1080/00397910802621731

文献信息

• BF3·OEt2 mediated regioselective deacetylation of polyacetoxyacetophenones and its application in the synthesis of natural products
  作者：T. Narender、K. Papi Reddy、Brijesh Kumar

  DOI：10.1016/j.tetlet.2008.05.020

  日期：2008.7

  We have developed an efficient method to regioselectively deacetylate polyacetoxyacetophenones using BF(3)center dot OEt(2) in excellent yields and demonstrated the application of the procedure in the synthesis of natural products. (C) 2008 Elsevier Ltd All rights reserved.
• NaOAc-Mediated Selective Deprotection of Aromatic Acetates and Its Application in the Synthesis of Natural Products
  作者：T. Narender、K. Papi Reddy、G. Madhur

  DOI：10.1080/00397910802621731

  日期：2009.5.7

  We have developed an efficient method to deacetylate the aromatic acetates using NaOAc in excellent yields and demonstrated the application of the procedure in the synthesis of natural products.