β-cyclodextrin

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: β-cyclodextrin
• 英文别名: (1S,3R,5R,6S,8S,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,49R)-5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,49-tridecol
• 化学式: C₄₂H₇₀O₃₄
• 分子量: 1119.0
• InChiKey: ADMHCAPIDLNHJS-IUGSFWGNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -14
• 重原子数：
  76
• 可旋转键数：
  7
• 环数：
  21.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  534
• 氢给体数：
  20
• 氢受体数：
  34

反应信息

• 作为反应物：
  描述：

  β-cyclodextrin 生成 maltoheptaose
  参考文献：
  名称：

  Apparent Production of Enzymatically Synthesized Amylose in DMSO by Means of Calcium Alginate Hydrogel Beads/DMSO System

  摘要：

  In this paper, we describe the apparent production of enzymatically synthesized amylose in DMSO by means of the calcium alginate hydrogel beads/DMSO system as the reaction field of the phosphorylase-catalyzed enzymatic polymerization. When the calcium alginate hydrogel beads including glucose-1-phosphate, maltoheptaose, and phosphorylase were suspended in DMSO and the system was slowly stirred at 40C for 12 h, the reaction proceeded to produce amylose, which eluted to the DMSO solution. The obtained amylose was purified by the treatment with ion-exchange resins, and its structure was confirmed by the 1H NMR spectrum. The time-course experiment in the present system revealed that the phosphorylase-catalyzed enzymatic polymerization was carried out for 15 min on the inside of the calcium alginate hydrogel beads and the produced amylose was gradually eluted to the surrounding DMSO solution. The comparison of the present system with the general enzymatic polymerization in aqueous buffer solution suggested that the yield and the degree of polymerization of amylose in the present system were comparable to those in aqueous buffer solution.

  DOI：

  10.1080/07328300902874787

文献信息

• Apparent Production of Enzymatically Synthesized Amylose in DMSO by Means of Calcium Alginate Hydrogel Beads/DMSO System
  作者：Hironori Izawa、Yoshiro Kaneko、Jun-ichi Kadokawa

  DOI：10.1080/07328300902874787

  日期：2009.5.22

  In this paper, we describe the apparent production of enzymatically synthesized amylose in DMSO by means of the calcium alginate hydrogel beads/DMSO system as the reaction field of the phosphorylase-catalyzed enzymatic polymerization. When the calcium alginate hydrogel beads including glucose-1-phosphate, maltoheptaose, and phosphorylase were suspended in DMSO and the system was slowly stirred at 40C for 12 h, the reaction proceeded to produce amylose, which eluted to the DMSO solution. The obtained amylose was purified by the treatment with ion-exchange resins, and its structure was confirmed by the 1H NMR spectrum. The time-course experiment in the present system revealed that the phosphorylase-catalyzed enzymatic polymerization was carried out for 15 min on the inside of the calcium alginate hydrogel beads and the produced amylose was gradually eluted to the surrounding DMSO solution. The comparison of the present system with the general enzymatic polymerization in aqueous buffer solution suggested that the yield and the degree of polymerization of amylose in the present system were comparable to those in aqueous buffer solution.