3,5-Di-tert-butyl-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]benzoic acid succinimidyl ester

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,5-Di-tert-butyl-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]benzoic acid succinimidyl ester
• 英文别名: (2,5-Dioxopyrrolidin-1-yl) 3,5-ditert-butyl-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]benzoate；(2,5-dioxopyrrolidin-1-yl) 3,5-ditert-butyl-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]benzoate
• 化学式: C₂₅H₃₇NO₈
• 分子量: 479.571
• InChiKey: ANUSWFMIXZFNBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  34
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2-[2-[2-[2-[3-[6-[3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]prop-1-ynyl]pyren-1-yl]prop-2-ynoxy]ethoxy]ethoxy]ethoxy]ethanamine 、 3,5-Di-tert-butyl-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]benzoic acid succinimidyl ester 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 20.0h， 以69%的产率得到
  参考文献：
  名称：

  Cyclodextrin-Isolated Alkynylpyrenes as UV-Stable and Blue-Light-Emitting Molecules Even in Condensed States

  摘要：

  Encapsulation of highly emissive alkynylpyrenes with permethylated alpha-cyclodextrin (PM-alpha-CD) followed by capping reaction yielded alkynylpyrene-based [3]rotaxanes. The [3]rotaxane emitted only blue light of monomeric pyrene under various circumstances such as lipophilic, hydrophilic, and even condensed states and exhibited extremely high stability for UV irradiation. These properties would result because PM-alpha-CD, like bulletproof glass, protected the alkynylpyrene core from the attack of another excited alkynylpyrene and singlet oxygen generated by the energy transfer from the excited alkynylpyrene.

  DOI：

  10.1021/acs.orglett.6b00420
• 作为产物：
  描述：

  3,5-二叔丁基-4-羟基苯甲酸 在 硫酸 、 potassium carbonate 、 N,N'-二环己基碳二亚胺 、 sodium hydroxide 作用下， 以 四氢呋喃 、 甲醇 、 水 、 丁酮 为溶剂， 反应 55.0h， 生成 3,5-Di-tert-butyl-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]benzoic acid succinimidyl ester
  参考文献：
  名称：

  Cyclodextrin-Isolated Alkynylpyrenes as UV-Stable and Blue-Light-Emitting Molecules Even in Condensed States

  摘要：

  Encapsulation of highly emissive alkynylpyrenes with permethylated alpha-cyclodextrin (PM-alpha-CD) followed by capping reaction yielded alkynylpyrene-based [3]rotaxanes. The [3]rotaxane emitted only blue light of monomeric pyrene under various circumstances such as lipophilic, hydrophilic, and even condensed states and exhibited extremely high stability for UV irradiation. These properties would result because PM-alpha-CD, like bulletproof glass, protected the alkynylpyrene core from the attack of another excited alkynylpyrene and singlet oxygen generated by the energy transfer from the excited alkynylpyrene.

  DOI：

  10.1021/acs.orglett.6b00420

文献信息

• Cyclodextrin-Isolated Alkynylpyrenes as UV-Stable and Blue-Light-Emitting Molecules Even in Condensed States
  作者：Masahiko Inouye、Atsushi Yoshizawa、Mari Shibata、Yuki Yonenaga、Kazuhisa Fujimoto、Takuma Sakata、Shinya Matsumoto、Motoo Shiro

  DOI：10.1021/acs.orglett.6b00420

  日期：2016.5.6

  Encapsulation of highly emissive alkynylpyrenes with permethylated alpha-cyclodextrin (PM-alpha-CD) followed by capping reaction yielded alkynylpyrene-based [3]rotaxanes. The [3]rotaxane emitted only blue light of monomeric pyrene under various circumstances such as lipophilic, hydrophilic, and even condensed states and exhibited extremely high stability for UV irradiation. These properties would result because PM-alpha-CD, like bulletproof glass, protected the alkynylpyrene core from the attack of another excited alkynylpyrene and singlet oxygen generated by the energy transfer from the excited alkynylpyrene.