2-(4-dioctylamino)phenyl-3-hydroxy-7-methoxy-4H-chromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2-(4-dioctylamino)phenyl-3-hydroxy-7-methoxy-4H-chromen-4-one
• 英文别名: 2-[4-(Dioctylamino)phenyl]-3-hydroxy-7-methoxychromen-4-one；2-[4-(dioctylamino)phenyl]-3-hydroxy-7-methoxychromen-4-one
• 化学式: C₃₂H₄₅NO₄
• 分子量: 507.714
• InChiKey: BLEDNXPSJCCBGG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10
• 重原子数：
  37
• 可旋转键数：
  17
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  59
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N,N-二-正-辛基苯胺 在 双氧水 、 sodium methylate 、 三氯氧磷 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 生成 2-(4-dioctylamino)phenyl-3-hydroxy-7-methoxy-4H-chromen-4-one
  参考文献：
  名称：

  New 3-hydroxyflavone derivatives for probing hydrophobic sites in microheterogeneous systems

  摘要：

  Nine new 3-hydroxyflavone derivatives as fluorescent molecular sensors having two well-separated emission bands were synthesized. These sensors can occupy well-determined locations and orientations in macromolecular ensembles, such as micelles due to their finely-tuned designs. These polarity-sensitive dyes can incorporate into the anhydrous hydrophobic core of aqueous micelles. (C) 2007 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tet.2007.07.074

文献信息

• New 3-hydroxyflavone derivatives for probing hydrophobic sites in microheterogeneous systems
  作者：Turan Ozturk、Andrey S. Klymchenko、Asli Capan、Sule Oncul、Simay Cikrikci、Sule Taskiran、Bahar Tasan、F. Betul Kaynak、Suheyla Ozbey、Alexander P. Demchenko

  DOI：10.1016/j.tet.2007.07.074

  日期：2007.10

  Nine new 3-hydroxyflavone derivatives as fluorescent molecular sensors having two well-separated emission bands were synthesized. These sensors can occupy well-determined locations and orientations in macromolecular ensembles, such as micelles due to their finely-tuned designs. These polarity-sensitive dyes can incorporate into the anhydrous hydrophobic core of aqueous micelles. (C) 2007 Published by Elsevier Ltd.