trehalose 6-acetate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: trehalose 6-acetate
• 英文别名: Glc6Ac(a1-1a)Glc；[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl acetate
• 化学式: C₁₄H₂₄O₁₂
• 分子量: 384.337
• InChiKey: GYATTZBAFLRLML-LOUZWEESSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  196
• 氢给体数：
  7
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  trehalose 6,6'-diacetate 在 Candida antarctica 、 水 作用下， 以 乙酸乙酯 为溶剂， 反应 24.0h， 生成 trehalose 6-acetate 、 海藻糖
  参考文献：
  名称：

  具有纳米结构形态的酶衍生的含糖自组装有机凝胶。

  摘要：

  DOI：

  10.1002/anie.200600989

文献信息

• Stabilization of biomolecules using sugar polymers
  申请人：The Regents of the University of California

  公开号：US10543280B2

  公开（公告）日：2020-01-28

  Compositions and methods for stabilizing biomolecules are disclosed. Specifically, the compositions include novel homopolymers or copolymers containing trehalose side chains conjugated to biomolecules. When such homopolymers or copolymers are placed in close proximity to biomolecules, such as proteins, the homopolymers or copolymers protect and/or stabilize the biomolecule. The compositions and methods may be suitable for use in various industries such as healthcare (pharmaceuticals), molecular biology, biofuels, paper, personal care, detergent, photographic, rubber, brewing, dairy and food processing industries.

  本发明公开了用于稳定生物分子的组合物和方法。具体来说，这些组合物包括新型均聚物或共聚物，这些均聚物或共聚物含有与生物大分子共轭的三卤糖侧链。当这种均聚物或共聚物与蛋白质等生物大分子紧密接触时，均聚物或共聚物可保护和/或稳定生物大分子。这些组合物和方法可适用于各种行业，如医疗保健（制药）、分子生物学、生物燃料、造纸、个人护理、洗涤剂、照相、橡胶、酿造、乳品和食品加工行业。
• STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US20140377838A1

  公开（公告）日：2014-12-25

  Compositions and methods for stabilizing biomolecules are disclosed. Specifically, the compositions include novel homopolymers or copolymers containing trehalose side chains conjugated to biomolecules. When such homopolymers or copolymers are placed in close proximity to biomolecules, such as proteins, the homopolymers or copolymers protect and/or stabilize the biomolecule. The compositions and methods may be suitable for use in various industries such as healthcare (pharmaceuticals), molecular biology, biofuels, paper, personal care, detergent, photographic, rubber, brewing, dairy and food processing industries.
• US9901648B2
  申请人：——

  公开号：US9901648B2

  公开（公告）日：2018-02-27
• Enzymatically Derived Sugar-Containing Self-Assembled Organogels with Nanostructured Morphologies
  作者：George John、Guangyu Zhu、Jun Li、Jonathan S. Dordick

  DOI：10.1002/anie.200600989

  日期：2006.7.17