(N-methylglucose)imine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (N-methylglucose)imine
• 英文别名: 6-Methyliminohexane-1,2,3,4,5-pentol
• 化学式: C₇H₁₅NO₅
• 分子量: 193.2
• InChiKey: RKMBAGSNCOGHAE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  114
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  2,3,4,5,6-pentahydroxy-hexanal 、 甲胺 在 sodium methylate 作用下， 以 甲醇 为溶剂， 10.0~30.0 ℃ 、5.0 MPa 条件下， 反应 1.5h， 以99%的产率得到(N-methylglucose)imine
  参考文献：
  名称：

  一种N-烷基葡萄糖亚胺的制备方法

  摘要：

  本发明提供了一种生产N‑烷基葡萄糖亚胺的制备工艺。该工艺以N‑烷基胺和葡萄糖作为起始原料，采用甲醇钠或者乙醇钠消耗反应生成的水，打破了反应的平衡，促进了反应向正方向进行，实现了葡萄糖的完全转化。甲醇钠和乙醇钠与水反应可以在较低的温度下快速进行，最大程度的限制了美拉德副反应的进行。另外，甲醇钠和乙醇钠还是一类有机强碱，它可以高效催化N‑烷基胺和葡萄糖发生反应。采用该工艺制备N‑烷基葡萄糖亚胺具有操作简便、成本低，可工业化生产的优点。该工艺发明的提出，为采用固定床加氢工艺制备N‑烷基葡萄糖胺奠定了坚实的基础。

  公开号：

  CN106986900B

文献信息

• Dialysate of peritoneal dialysis and its preparation method
  申请人：Sakai Asahi

  公开号：US20070199898A1

  公开（公告）日：2007-08-30

  An aqueous solution of electrolytes, a sugar osmotic agent and a physiologically safe salt of a reductive sulfur oxy-acid. Alternatively, the dialysate comprises an aqueous solution of electrolytes, a salt of a reductive sulfur oxy-acid, and osmotic agents which contain an oncotic agent other than a sugar osmotic agent.

  一种含有电解质、糖渗透剂和还原性硫氧酸盐的水溶液。或者，透析液包括含有电解质、还原性硫氧酸盐和渗透剂的水溶液，其中渗透剂包含除糖渗透剂以外的渗透剂。
• CIS DI-AHL MODIFIED CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS
  申请人：Das Kausik

  公开号：US20120122073A1

  公开（公告）日：2012-05-17

  The invention is composition comprising red blood cells in an aqueous suspension medium and one or more cis di-ahls; wherein more than 6 percent by weight of the hemoglobin in the red blood cells is S-Alc glycated hemoglobin. In another embodiment, the invention is a method comprising contacting red blood cells in a suspension medium having a concentration of S-Alc glycated hemoglobin of greater than 6 percent by weight of the hemoglobin in the red blood cells with a sufficient amount of one or more cis di-ahls such that the concentration of S-Alc glycated hemoglobin in resulting composition as measured by high pressure liquid chromatography, immunoassay and boronate affinity methods is consistent.
• METHOD OF PREPARING CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS
  申请人：Das Kausik

  公开号：US20120129147A1

  公开（公告）日：2012-05-24

  By way of summary, the present invention meets some or all of the above needs by providing in a first aspect a method comprising contacting red blood cells in a suspension medium containing mannose under conditions such that the concentration of S-Alc glycated hemoglobin is increased to greater than about 6 percent by weight of the hemoglobin in the red blood cells. Preferably the suspension medium is an aqueous suspension medium. In preferred embodiments, the method is performed at about ambient temperature, 18° C. to about 23° C.
• US7361513B2
  申请人：——

  公开号：US7361513B2

  公开（公告）日：2008-04-22
• US8216776B2
  申请人：——

  公开号：US8216776B2

  公开（公告）日：2012-07-10