乙酮,1-(2,3,5-三甲苯基)- | 15764-15-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 乙酮,1-(2,3,5-三甲苯基)-
• 英文名称: 1-(2,3,5-Trimethylphenyl)ethan-1-one
• 英文别名: 1-(2,3,5-trimethylphenyl)ethanone
• CAS: 15764-15-5
• 化学式: C₁₁H₁₄O
• 分子量: 162.23
• InChiKey: BYVMZXUXDZTORD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND
  申请人：Matsuda Koji

  公开号：US20090318702A1

  公开（公告）日：2009-12-24

  The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, the present invention provides, for example, compounds represented by the formulas (6), (7-1), (7-2) and (8): wherein R is a fluorine atom or a methoxy group, R 1 is a C 1 -C 4 alkyl group, R 2 is a hydroxyl-protecting group, and X 2 is a halogen atom, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.

  本发明提供了一种化合物，可用作具有整合酶抑制活性的抗HIV药物的合成中间体，其生产方法，以及使用该合成中间体制备抗HIV药物的生产方法。具体来说，本发明提供了例如由以下公式表示的化合物（6），（7-1），（7-2）和（8）： 其中R为氟原子或甲氧基，R1为C1-C4烷基，R2为羟基保护基，X2为卤原子，其生产方法，以及使用该合成中间体制备抗HIV药物的生产方法。
• NOVEL PROCESS
  申请人：Bachmann Stephan

  公开号：US20110313196A1

  公开（公告）日：2011-12-22

  The present invention relates to a process for the preparation of benzamide derivatives which are useful as intermediates in the preparation of pharmaceutically active compounds.

  本发明涉及一种制备苯甲酰胺衍生物的方法，这些衍生物在制备药用活性化合物的中间体中很有用。
• METHOD FOR PRODUCING 4-OXOQUINOLINE COMPOUND
  申请人：Matsuda Koji

  公开号：US20090036684A1

  公开（公告）日：2009-02-05

  The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, for example, a compound represented by the formula (2′): wherein R is a fluorine atom or a methoxy group, and R 400 is a hydrogen atom or a C 1 -C 4 alkyl group, or a salt thereof, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.

  本发明提供了一种化合物，可用作抗HIV剂的合成中间体，具有整合酶抑制活性，以及其生产方法和使用该合成中间体生产抗HIV剂的方法。具体而言，例如，化合物由式（2'）表示：其中R为氟原子或甲氧基，R400为氢原子或C1-C4烷基，或其盐，以及其生产方法和使用该合成中间体生产抗HIV剂的方法。
• DENDRITIC AND STAR-SHAPED CONTRAST AGENTS FOR MEDICAL DEVICES AND BIOABSORBABLE RADIOPAQUE BULK MATERIAL AND METHOD FOR PRODUCING SAME
  申请人：Zhao Jonathon Z.

  公开号：US20080177102A1

  公开（公告）日：2008-07-24

  In accordance with the present invention, a high intensity radiopaque contrast agent is disclosed. The agent may be coated on or incorporated within bulk materials, which may then be subsequently utilized to fabricate a radiopaque medical device. Primary effects through chemistry include higher radiopaque concentrations per unit weight of the radiopaque element or agent. Secondary effects include selective placement of the radiopaque elements which may further enhance the radiopacity of the device with reduced requirements of the radiopaque agent. Such a radiopaque contrast agent may be produced in various forms such as a dendrimer and/or incorporated as the end groups of polymeric chain. In addition one can incorporate biological and/or pharmaceutical agents in combination with the present invention.
• UV PATTERNABLE POLYMER BLENDS FOR ORGANIC THIN-FILM TRANSISTORS
  申请人：Corning Incorporated

  公开号：US20210341838A1

  公开（公告）日：2021-11-04

  A polymer blend includes at least one organic semiconductor (OSC) polymer, at least one crosslinker, and at least one photoinitiator, such that the at least one OSC polymer is a diketopyrrolopyrrole-fused thiophene polymeric material, the fused thiophene being beta-substituted, and such that the crosslinker includes at least one of: acrylates, epoxides, oxetanes, alkenes, alkynes, azides, thiols, allyloxysilanes, phenols, anhydrides, amines, cyanate esters, isocyanate esters, silyl hydrides, cinnamates, coumarins, fluorosulfates, silyl ethers, or a combination thereof.