Synthesis of 2-Tetrazolylmethyl-2,3,4,9-tetrahydro-1H-β-carbolines by a One-Pot Ugi-Azide/Pictet–Spengler Process
摘要:
A series of novel 2-tetrazolylmethyl-2,3,4,9-tetrahydro-1H--carbolines were prepared in good to excellent overall yields by an efficient MW-assisted one-pot Ugi-azide/Pictet-Spengler process. This work describes the first synthesis of compounds including both 1,5-disubstituted 1H-tetrazole and 2,3,4,9-tetrahydro-1H--carboline heterocyclic systems.
Synthesis of 2-Tetrazolylmethyl-2,3,4,9-tetrahydro-1H-β-carbolines by a One-Pot Ugi-Azide/Pictet–Spengler Process
摘要:
A series of novel 2-tetrazolylmethyl-2,3,4,9-tetrahydro-1H--carbolines were prepared in good to excellent overall yields by an efficient MW-assisted one-pot Ugi-azide/Pictet-Spengler process. This work describes the first synthesis of compounds including both 1,5-disubstituted 1H-tetrazole and 2,3,4,9-tetrahydro-1H--carboline heterocyclic systems.
Synthesis of 2-Tetrazolylmethyl-2,3,4,9-tetrahydro-1H-β-carbolines by a One-Pot Ugi-Azide/Pictet–Spengler Process
作者:Laurent El Kaim、Rocío Gámez-Montaño、Luis Cárdenas-Galindo、Alejandro Islas-Jácome、Nancy Alvarez-Rodríguez
DOI:10.1055/s-0033-1340051
日期:——
A series of novel 2-tetrazolylmethyl-2,3,4,9-tetrahydro-1H--carbolines were prepared in good to excellent overall yields by an efficient MW-assisted one-pot Ugi-azide/Pictet-Spengler process. This work describes the first synthesis of compounds including both 1,5-disubstituted 1H-tetrazole and 2,3,4,9-tetrahydro-1H--carboline heterocyclic systems.