3-aminophenol-formaldehyde alcohol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-aminophenol-formaldehyde alcohol
• 英文别名: 2-amino-6-hydroxybenzaldehyde；3-Aminophenol-Formaldehyde；aminophenol-formaldehyde
• 化学式: C₇H₇NO₂
• mdl: MFCD16999406
• 分子量: 137.138
• InChiKey: GRJNSCLXSLEWAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-aminophenol-formaldehyde alcohol 、 二碳酸二叔丁酯 在 4-二甲氨基吡啶 silica gel 、 ethyl acetate hexanes 作用下， 以 四氢呋喃 为溶剂， 反应 18.0h， 以to give 50 mg (14%) of tert-butyl (2-formyl-3-hydroxyphenyl)carbamate的产率得到Tert-butyl (2-formyl-3-hydroxyphenyl)carbamate
  参考文献：
  名称：

  COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN

  摘要：

  本文提供了化合物和制药组合物，适用于作为血红蛋白调节剂，其制备的方法和中间体，以及用于治疗通过血红蛋白介导的疾病和需要组织和/或细胞氧合的疾病的方法。

  公开号：

  US20160046613A1
• 作为产物：
  描述：

  吲哚洛尔 在 氧气 作用下， 生成 3-aminophenol-formaldehyde alcohol 、 carboxysalicylaldehyde 、 、
  参考文献：
  名称：

  Criado; Martire; Allegretti, Pharmazie, 2003, vol. 58, # 8, p. 551 - 553

  摘要：

  DOI：

文献信息

• Wine stabilization using immobilized phenolic compounds or tannic acid
  申请人：Corning Glass Works

  公开号：EP0118990A2

  公开（公告）日：1984-09-19

  A process for stabilizing wine is characterized by: a) immobilizing tannic acid or a phenolic compound; b) contacting a wine having components which causes haze formation upon heating with the immobolized tannic acid or the immobilized phenolic compound for a period sufficient to remove the desired amount of haze components; and c) separating the treated wine from the immobilized tannic acid or the immobilized phenolic compound.

  葡萄酒稳定工艺的特点是 a) 固定单宁酸或酚类化合物； b) 将具有在加热时会导致雾化形成的成分的葡萄酒与固定化单宁酸或固定化酚类化合物接触，接触时间足以去除所需量的雾化成分；以及 c) 将处理过的葡萄酒与固定化单宁酸或固定化酚类化合物分离。
• FINE ZINC OXIDE PARTICLES, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF
  申请人：NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD.

  公开号：EP0768277A1

  公开（公告）日：1997-04-16

  A process for producing zinc oxide fine particles comprising heating a mixture comprising a zinc source, a carboxyl-containing compound, and an alcohol; a process for producing zinc oxide-polymer composite particles, which comprises heating a mixture comprising a zinc source, a carboxyl-containing compound, a polymer, and an alcohol at a temperature of 100°C or higher; a process for producing inorganic compound particles having on their surface a cluster of thin plate like zinc oxide crystals with their tip projecting outward, which comprises heating a mixture comprising a zinc source, a carboxyl-containing compound, lactic acid or a compound thereof, and an alcohol at a temperature of 100°C or higher; a process for producing zinc oxide-based particles comprising heating a mixture comprising a zinc source, a carboxyl-containing compound, at least one element additive selected from the group consisting of the group IIIB metal elements and the group IVB metal elements, and an alcohol at a temperature of 100°C or higher; zinc oxide-based fine particles obtained by these processes; and uses of the zinc oxide-based fine particles.

  一种生产氧化锌微粒的工艺，包括加热由锌源、含羧基化合物和醇组成的混合物；一种生产氧化锌-聚合物复合微粒的工艺，包括在100℃或更高温度下加热由锌源、含羧基化合物、聚合物和醇组成的混合物；一种生产无机化合物颗粒的工艺，该无机化合物颗粒表面有一簇尖端向外突出的薄板状氧化锌晶体，该工艺包括在 100°C 或更高温度下加热由锌源、含羧基化合物、乳酸或其化合物和醇组成的混合物；一种生产氧化锌基微粒的工艺，包括在 100℃或更高温度下加热由锌源、含羧基化合物、至少一种选自 IIIB 族金属元素和 IVB 族金属元素组成的组的元素添加剂以及醇组成的混合物；通过这些工艺获得的氧化锌基微粒；以及氧化锌基微粒的用途。
• Zinc oxide-based fine particles, process for producing the same, and use thereof
  申请人：NIPPON SHOKUBAI CO., LTD.

  公开号：EP0893409A1

  公开（公告）日：1999-01-27

  A process for producing zinc oxide fine particles comprising heating a mixture comprising a zinc source, a carboxyl-containing compound, and an alcohol; a process for producing zinc oxide-polymer composite particles, which comprises heating a mixture comprising a zinc source, a carboxyl-containing compound, a polymer, and an alcohol at a temperature of 100°C or higher; a process for producing inorganic compound particles having on their surface a cluster of thin plate like zinc oxide crystals with their tip projecting outward, which comprises heating a mixture comprising a zinc source, a carboxyl-containing compound, lactic acid or a compound thereof, and an alcohol at a temperature of 100°C or higher; a process for producing zinc oxide-based particles comprising heating a mixture comprising a zinc source, a carboxyl-containing compound, at least one element additive selected from the group consisting of the group IIIB metal elements and the group IVB metal elements, and an alcohol at a temperature of 100°C or higher; zinc oxide-based fine particles obtained by these processes; and uses of the zinc oxide-based fine particles.

  一种生产氧化锌微粒的工艺，包括加热由锌源、含羧基化合物和醇组成的混合物；一种生产氧化锌-聚合物复合微粒的工艺，包括在100℃或更高温度下加热由锌源、含羧基化合物、聚合物和醇组成的混合物；一种生产无机化合物颗粒的工艺，该无机化合物颗粒表面有一簇尖端向外突出的薄板状氧化锌晶体，该工艺包括在 100°C 或更高温度下加热由锌源、含羧基化合物、乳酸或其化合物和醇组成的混合物；一种生产氧化锌基微粒的工艺，包括在 100℃或更高温度下加热由锌源、含羧基化合物、至少一种选自 IIIB 族金属元素和 IVB 族金属元素组成的组的元素添加剂以及醇组成的混合物；通过这些工艺获得的氧化锌基微粒；以及氧化锌基微粒的用途。
• COMPOSITION, PARTICULATE MATERIALS AND METHODS FOR MAKING PARTICULATE MATERIALS
  申请人：The University of Queensland

  公开号：EP3659590A1

  公开（公告）日：2020-06-03

  Particulate material comprising rough mesoporous hollow nanoparticles. The rough mesoporous hollow nanoparticles may comprise a mesoporous shell, the external surface of which has projections thereon, the projections having smaller sizes than the particle size. The particulate material may be used to deliver active agents, such as insecticides and pesticides. The active agents can enter into the hollow core of the particles and be protected from degradation by sunlight. The rough surface of the particles retains the particles on plant leaves or animal hair. Methods for forming the particles are also described. Carbon particles and methods for forming carbon particles are also described.

  由粗糙介孔空心纳米颗粒组成的颗粒材料。粗糙介孔空心纳米颗粒可包括介孔外壳，其外表面有凸起，凸起的尺寸小于颗粒尺寸。颗粒材料可用于输送活性剂，如杀虫剂和农药。活性剂可以进入颗粒的中空内核，免受阳光照射而降解。颗粒的粗糙表面可将颗粒留在植物叶片或动物毛发上。此外，还介绍了形成颗粒的方法。还介绍了碳颗粒和形成碳颗粒的方法。
• Compounds and uses thereof for the modulation of hemoglobin
  申请人：Global Blood Therapeutics, Inc.

  公开号：US10017491B2

  公开（公告）日：2018-07-10

  Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.

  本文提供了适合作为血红蛋白调节剂的化合物和药物组合物、制备它们的方法和中间体，以及将它们用于治疗由血红蛋白介导的疾病和可从组织和/或细胞氧合中获益的疾病的方法。