3,4-di-(1-ethoxyethoxy)-benzaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3,4-di-(1-ethoxyethoxy)-benzaldehyde
• 英文别名: 3,4-bis(2-ethoxyethoxy)benzaldehyde
• 化学式: C₁₅H₂₂O₅
• 分子量: 282.337
• InChiKey: SSVPZVUKJJGFSY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.33
• 重原子数：
  20.0
• 可旋转键数：
  11.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  53.99
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  3,4-di-(1-ethoxyethoxy)-benzaldehyde 在 potassium cyanide 、 tetraphosphorus decasulfide 作用下， 以 1,4-二氧六环 、 乙醇 、 水 为溶剂， 反应 9.0h， 生成
  参考文献：
  名称：

  The Synthesis of Novel Asymmetrical Benzoins and Bis(dithiobenzil) Metal Complex Dyes Containing Ethoxyethoxy Groups and Their Absorption Characteristics

  摘要：

  Asymmetrical bis(dithiobenzil) metal complex (BMC), as a NIR(Near Infra-Red) absorbing dye, was synthesized via preparation of asymmetric benzoin intermediates. Four synthesized dyes were characterized by elemental analyses and GC-Mass, H-1-NMR(nuclear magnetic resonance) analysis. The absorption characteristics of the synthesized dyes in the NIR region were measured using UV-VIS spectrophotometer. Maximum absorbing wavelength was shifted depending on the character and position of substituents in the bis(dithobenzil) metal complex.

  DOI：

  10.1080/15421406.2012.691676
• 作为产物：
  描述：

  乙烯基乙醚 、 3,4-二羟基苯甲醛 在 4-甲基苯磺酸吡啶 作用下， 以 乙醚 为溶剂， 反应 72.0h， 以91%的产率得到3,4-di-(1-ethoxyethoxy)-benzaldehyde
  参考文献：
  名称：

  通过三种不同的策略合成新的生物合成重要的二芳基庚烷及其氧杂和氟类似物

  摘要：

  摘要 Wittig、aldol 和 Wittig-Horner 反应已被用于合成新的二芳基庚烷类化合物，它们是植物中苯菲酮生物合成的假定中间体。与其他方法相比，Wittig-Horner 方法是最合适的，并且产生了显着更高的产量。

  DOI：

  10.1081/scc-120016367

文献信息

• Synthesis of New Biosynthetically Important Diarylheptanoids and Their Oxa- and Fluoro- Analogues by Three Different Strategies
  作者：Alexander Baranovsky、Bettina Schmitt、Daniel J. Fowler、Bernd Schneider

  DOI：10.1081/scc-120016367

  日期：2003.1.4

  Abstract Wittig, aldol and Wittig-Horner reactions have been used to synthesize new diarylheptanoids, which are putative intermediates in phenylphenalenone biosynthesis in plants. The Wittig-Horner approach was most suitable and gave significantly higher yields in comparison with other methods.

  摘要 Wittig、aldol 和 Wittig-Horner 反应已被用于合成新的二芳基庚烷类化合物，它们是植物中苯菲酮生物合成的假定中间体。与其他方法相比，Wittig-Horner 方法是最合适的，并且产生了显着更高的产量。
• The Synthesis of Novel Asymmetrical Benzoins and Bis(dithiobenzil) Metal Complex Dyes Containing Ethoxyethoxy Groups and Their Absorption Characteristics
  作者：Na-Rim Kim、Jae-Hong Choi

  DOI：10.1080/15421406.2012.691676

  日期：2012.9.19

  Asymmetrical bis(dithiobenzil) metal complex (BMC), as a NIR(Near Infra-Red) absorbing dye, was synthesized via preparation of asymmetric benzoin intermediates. Four synthesized dyes were characterized by elemental analyses and GC-Mass, H-1-NMR(nuclear magnetic resonance) analysis. The absorption characteristics of the synthesized dyes in the NIR region were measured using UV-VIS spectrophotometer. Maximum absorbing wavelength was shifted depending on the character and position of substituents in the bis(dithobenzil) metal complex.