10-hydroxystrictosamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 10-hydroxystrictosamide
• 英文别名: (1S,18S,19R,20S)-19-ethenyl-7-hydroxy-18-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15-pentaen-14-one
• 化学式: C₂₆H₃₀N₂O₉
• 分子量: 514.532
• InChiKey: ZDYTVCFDZWEYRR-KDLXYAJASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  37
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 10-hydroxystrictosamide 在 吡啶 作用下， 生成 10-hydroxystrictosamide pentaacetate
  参考文献：
  名称：

  Isolation, Partial Synthesis and Stereochemical Study of 10-Hydroxystrictosamide, a Constituent of Nauclea orientalis in Thailand

  摘要：

  From the Rubiaceous plant, Nauclea orientalis, in Thailand, seven non-alkaloidal and two glycosidic indole compounds were isolated. 10-Hydroxystrictosamide (5) and its pentaacetyl derivative (11) were prepared to determine the C3 stereochemistry.

  DOI：

  10.3987/com-98-s12
• 作为产物：
  描述：

  开联番木鳖苷 、 5-羟基色胺盐酸盐 在 sodium carbonate 作用下， 生成 10-hydroxystrictosamide 、 10-hydroxyvincoside lactam
  参考文献：
  名称：

  Isolation, Partial Synthesis and Stereochemical Study of 10-Hydroxystrictosamide, a Constituent of Nauclea orientalis in Thailand

  摘要：

  From the Rubiaceous plant, Nauclea orientalis, in Thailand, seven non-alkaloidal and two glycosidic indole compounds were isolated. 10-Hydroxystrictosamide (5) and its pentaacetyl derivative (11) were prepared to determine the C3 stereochemistry.

  DOI：

  10.3987/com-98-s12

文献信息

• Isolation, Partial Synthesis and Stereochemical Study of 10-Hydroxystrictosamide, a Constituent of Nauclea orientalis in Thailand
  作者：Hiromitsu Takayama、Osamu Ohmori、Masayo Sakai、Michiko Funahashi、Mariko Kitajima、Dammrong Santiarworn、Boonsom Liawruangrath、Norio Aimi

  DOI：10.3987/com-98-s12

  日期：——

  From the Rubiaceous plant, Nauclea orientalis, in Thailand, seven non-alkaloidal and two glycosidic indole compounds were isolated. 10-Hydroxystrictosamide (5) and its pentaacetyl derivative (11) were prepared to determine the C3 stereochemistry.