二甲基蒽-1,9-二甲酸酯 | 87919-72-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 二甲基蒽-1,9-二甲酸酯
• 英文名称: 1,9-Anthracendicarbonsaeure-dimethylester
• 英文别名: dimethyl anthracene-1,9-dicarboxylate；anthracene-1,9-dicarboxylic acid dimethyl ester；Anthracen-1,9-dicarbonsaeure-dimethylester
• CAS: 87919-72-0
• 化学式: C₁₈H₁₄O₄
• 分子量: 294.307
• InChiKey: UCXVRPZYVHFUHP-UHFFFAOYSA-N

物化性质

• 熔点：
  143-147 °C(Solv: methanol (67-56-1))
• 沸点：
  466.7±18.0 °C(Predicted)
• 密度：
  1.260±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  二甲基蒽-1,9-二甲酸酯 在 吡啶 、 lithium aluminium tetrahydride 、 乙醚 、 三溴化磷 、 苯基锂 、 苯 作用下， 生成 1,2-二氢醋蒽烯
  参考文献：
  名称：

  Notes - A Synthesis of Aceanthrene

  摘要：

  DOI：

  10.1021/jo01100a608
• 作为产物：
  描述：

  1,2-苯并苊醌 在 4-ethyl-1-methyl-4H-[1,2,4]-triazol-1-ium iodide 、 水 、 magnesium sulfate 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 四氢呋喃 为溶剂， 反应 32.0h， 生成 二甲基蒽-1,9-二甲酸酯
  参考文献：
  名称：

  Organocatalytic Aerobic Oxidative Cleavage of Cyclic 1,2-Diketones

  摘要：

  The first organocatalytic aerobic oxidative cleavage of cyclic 1,2-diketones is reported. The reaction occurs in either aqueous or alcoholic media and is promoted by a simple N-heterocyclic carbene catalyst derived from a 1,2,4-triazolium ion. No strong oxidants are required. The application of the process in a one-pot synthesis of a cyclic anhydride is also possible.

  DOI：

  10.1055/s-0033-1338494

文献信息

• Dihydrodibenzisoquinolinediones
  申请人：Knoll Aktiengesellschaft

  公开号：US05703089A1

  公开（公告）日：1997-12-30

  Novel bis-1,2-dihydro-3H-dibenzisoquinoline-1,3-diones and their salts, processes for their preparation, pharmaceutical compositions containing them and methods of using them to treat malignancies, mainly human solid tumor carcinomas.

  新型bis-1,2-二氢-3H-二苯并异喹啉-1,3-二酮及其盐，其制备方法，含有它们的药物组合物以及使用它们治疗恶性肿瘤，主要是人类实体肿瘤癌症的方法。
• Xenon and nitrous oxide do not depress cardiac function in an isolated rat heart model
  作者：Harumi Nakayama、Hiroshi Takahashi、Naomitsu Okubo、Masayuki Miyabe、Hidenori Toyooka

  DOI：10.1007/bf03017325

  日期：2002.4

  Purpose: To examine the inotropic and chronotropic effects of xenon (Xe) and nitrous oxide (N2O) compared with nitrogen (N-2) on isolated rat hearts. The differences between Xe and N2O were also compared.Methods: The effects of Xe, N2O and N-2 on coronary perfusion pressure (CPP), heart rate, left ventricular developed pressure (LVDP) and double product (DP) were examined in isolated rat hearts perfused at constant flow (10 mL.min(-1)). Following stabilization and baseline measurement with 95% O-2 (plus 5% CO2), the heart was exposed to buffer equilibrated with one of three test gases; 50% N-2 with 4596 O-2 (Group N-2: n=9),50% Xe with 45% O-2 (Group Xe: n=9), or 50% N2O with 45% O-2 (Group N2O: n=9) for 30 min. Measurements were performed in the last minute of exposure to the test gases.Results: Gas exposure in all three groups decreased O-2 delivery (-50%), CPP (-11%), LVDP (-30%) and DP (-44%) compared with baseline values (P < 0.001). However, there were no differences among the groups.Conclusion: Our data suggest that cardiac contractility was decreased by the effects of reduced O-2 delivery but both Xe and N2O did not cause further cardiac depressant effects compared to N-2 in this experimental model.
• Neugebauer, Wolfgang; Clark, Timothy; Schleyer, Paul von Rague, Chemische Berichte, 1983, vol. 116, # 10, p. 3283 - 3292
  作者：Neugebauer, Wolfgang、Clark, Timothy、Schleyer, Paul von Rague

  DOI：——

  日期：——
• Kardos, Chemische Berichte, 1913, vol. 46, p. 2090
  作者：Kardos

  DOI：——

  日期：——
• NEUGEBAUER, W.;CLARK, T.;SCHLEYER, P. R., CHEM. BER., 1983, 116, N 10, 3283-3292
  作者：NEUGEBAUER, W.、CLARK, T.、SCHLEYER, P. R.

  DOI：——

  日期：——