(E)-cinnamyl (E)-ferulate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-cinnamyl (E)-ferulate
• 英文别名: (e)-Cinnamyl-(e)-ferulate；[(E)-3-phenylprop-2-enyl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
• 化学式: C₁₉H₁₈O₄
• 分子量: 310.35
• InChiKey: KRGYARJAIVTGGV-JPFJJCCVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  α-chloroacetate de cinnamyle 以 二氯甲烷 、 苯 为溶剂， 反应 16.0h， 生成 (E)-cinnamyl (E)-ferulate
  参考文献：
  名称：

  Mali; Papalkar, Journal of Chemical Research - Part S, 2001, # 10, p. 433 - 435

  摘要：

  DOI：

文献信息

• Mahajan, Rajesh P; Patil, Ulhas K; Patil, Shamkant L, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2007, vol. 46, # 9, p. 1459 - 1465
  作者：Mahajan, Rajesh P、Patil, Ulhas K、Patil, Shamkant L

  DOI：——

  日期：——
• PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH
  申请人：Manuka Health New Zealand Limited

  公开号：EP3169321A1

  公开（公告）日：2017-05-24
• Propolis and Extracts Thereof for the Treatment of Skin Cancers and Improvement of Skin Health
  申请人：Manuka Health New Zealand Limited

  公开号：US20170209499A1

  公开（公告）日：2017-07-27

  This invention provides pharmaceutical and cosmeceutical compositions, including anti-skin cancer compositions, N containing propolis and cyclodextrin, and compositions comprising one or more compounds present in propolis, including compositions comprising one or more compounds present as an inclusion complex with cyclodextrin. Methods of using such compounds and compositions, in particular in the treatment or prevention of skin cancers and skin disorders, and in enhancing skin health, are also provided.
• [EN] PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH<br/>[FR] PROPOLIS ET EXTRAITS DE PROPOLIS POUR TRAITER LES CANCERS DE LA PEAU ET AMÉLIORER LA SANTÉ DE LA PEAU
  申请人：MANUKA HEALTH NEW ZEALAND LTD

  公开号：WO2016010440A1

  公开（公告）日：2016-01-21

  This invention provides pharmaceutical and cosmeceutical compositions, including anti-skin cancer compositions, containing propolis and cyclodextrin, and compositions comprising one or more compounds present in propolis, including compositions comprising one or more compounds present as an inclusion complex with cyclodextrin. Methods of using such compounds and compositions, in particular in the treatment or prevention of skin cancers and skin disorders, and in enhancing skin health, are also provided.
• [EN] THERAPEUTIC COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSITIONS THÉRAPEUTIQUES ET LEURS UTILISATIONS
  申请人：MANUKA HEALTH NEW ZEALAND LTD

  公开号：WO2017164750A1

  公开（公告）日：2017-09-28

  This invention provides pharmaceutical and cosmeceutical compositions, including anti-epithelial cancer compositions, containing glyceride compounds, and compositions comprising one or more of these compounds. Methods of preparing and using such compositions, in particular in the treatment or prevention of epithelial cancers, such as skin cancers, gastrointestinal cancers, and skin disorders, are also provided.