(3-ethylcyclohexyl)methanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3-ethylcyclohexyl)methanol
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: OBCVXHDACNJTJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1,6-庚二烯 、 氯化二乙基铝 在 titanium(IV) isopropylate 、 氧气 作用下， 生成 (3-ethylcyclohexyl)methanol
  参考文献：
  名称：

  Titanium-Catalyzed Cascade Carboalumination of Dienes and Trienes

  摘要：

  DOI：

  10.1021/ja00097a073

文献信息

• [EN] BRIDGED COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS<br/>[FR] COMPOSÉS PONTÉS POUR LE TRAITEMENT DES INFECTIONS BACTÉRIENNES
  申请人：MERCK SHARP & DOHME

  公开号：WO2016123146A1

  公开（公告）日：2016-08-04

  Novel bridged compounds are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antibacterial agents. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating bacterial infections and associated diseases and conditions.

  本文披露了新型的桥接化合物，以及它们的药用盐、水合物和前药。还披露了包含这些化合物的组合物，制备这些化合物的方法以及将这些化合物用作抗菌剂的方法。所披露的化合物、其药用盐、水合物和前药，以及包含这些化合物、盐、水合物和前药的组合物，对治疗细菌感染及相关疾病和症状是有用的。
• [EN] BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS<br/>[FR] COMPOSÉS BICYCLIQUES PONTÉS POUR LE TRAITEMENT DES INFECTIONS BACTÉRIENNES
  申请人：KYORIN SEIYAKU KK

  公开号：WO2013003383A1

  公开（公告）日：2013-01-03

  Novel bridged bicyclic compounds are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antibacterial agents. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating bacterial infections and associated diseases and conditions.

  本文披露了新型桥环双环化合物，以及它们的药用盐、水合物和前药。还披露了包含这些化合物的组合物，制备这些化合物的方法以及将这些化合物用作抗菌剂的方法。所披露的化合物、其药用盐、水合物和前药，以及包含这些化合物、盐、水合物和前药的组合物，可用于治疗细菌感染及相关疾病和症状。
• BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS
  申请人：Fukuda Yasumichi

  公开号：US20140243302A1

  公开（公告）日：2014-08-28

  Novel bridged bicyclic compounds are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antibacterial agents. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating bacterial infections and associated diseases and conditions.

  本文披露了新型桥环双环化合物及其药学上可接受的盐、水合物和前药。还披露了包含这些化合物的组合物、制备这些化合物的方法以及将这些化合物用作抗菌剂的方法。披露的化合物、它们的药学上可接受的盐、水合物和前药，以及包含这些化合物、盐、水合物和前药的组合物，可用于治疗细菌感染及相关疾病和病情。
• Compounds for the treatment of bacterial infections
  申请人：Merck Sharp & Dohme Corp.

  公开号：EP3050888A1

  公开（公告）日：2016-08-03

  Novel bridged compounds of formula (I) are disclosed herein, along with their pharmaceutically acceptable salts and hydrates. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antibacterial agents. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating bacterial infections and associated diseases and conditions.

  本文公开了式 (I) 的新型桥联化合物及其药学上可接受的盐类和水合物。还公开了包含此类化合物的组合物、制备此类化合物的方法以及将此类化合物用作抗菌剂的方法。所公开的化合物、它们的药学上可接受的盐、水合物和原药，以及包含这些化合物、盐、水合物和原药的组合物，可用于治疗细菌感染及相关疾病和病症。
• US4231915A
  申请人：——

  公开号：US4231915A

  公开（公告）日：1980-11-04