1-[2-(2-(2-hydroxyethoxy)ethoxy)ethyl]-3-methylimidazolium chloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-[2-(2-(2-hydroxyethoxy)ethoxy)ethyl]-3-methylimidazolium chloride
• 英文别名: 2-[2-[2-(3-Methylimidazol-3-ium-1-yl)ethoxy]ethoxy]ethanol;chloride
• 化学式: C₁₀H₁₉N₂O₃*Cl
• 分子量: 250.725
• InChiKey: ZNBRINNPDVAXRK-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.66
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  47.5
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-[2-(2-(2-hydroxyethoxy)ethoxy)ethyl]-3-methylimidazolium chloride 在 六氟磷酸钾 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以95%的产率得到1-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-3-methyl-imidazolium hexafluorophosphate
  参考文献：
  名称：

  用于液相有机合成的亲水性聚（乙二醇）离子液体基质的环保快速合成。

  摘要：

  基于 1,3-二取代咪唑阳离子和氟化阴离子（BF4-、PF6-、(CF3SO2)2N- 或 NTf2-），已经合成和研究了新型亲水性聚（乙二醇）离子液体。使用聚焦微波反应器安全地实现了一系列典型的无溶剂反应，用于制备氯化咪唑前体，收率范围为 73% 至 94%，然后进行定量阴离子复分解交换。聚 (乙二醇)-离子液体基质还通过 NMR (1H, 13C)、质谱 (MS) 进行了表征，并在 25 °C 下测定了它们的动态粘度。这些聚（乙二醇）离子液相（PEG-ILPs）作为特定任务的离子液体是液相组合化学中合成应用的有前途的工具。

  DOI：

  10.1021/op020027y
• 作为产物：
  描述：

  N-甲基咪唑 、 2-氯乙氧基-2-乙氧基二乙醇 反应 60.0h， 以99.1%的产率得到1-[2-(2-(2-hydroxyethoxy)ethoxy)ethyl]-3-methylimidazolium chloride
  参考文献：
  名称：

  Liquid chromatography and characterization of ether-functionalized imidazolium ionic liquids on mixed-mode reversed-phase/cation exchange stationary phase

  摘要：

  摘要 制备了一种新的咪唑阳离子基离子液体（ILs）系列[CnOmmim]Cl，其烷基侧链上带有一个醚官能团。研究人员采用混合模式反相/阳离子交换固定相，以水-乙腈为流动相，研究了用高效液相色谱法（HPLC）分析离子液体的可能性。研究了保留因子、选择性和柱效等洗脱参数与流动相组成和 pH 值的函数关系。通过元素分析、红外光谱、紫外光谱和 1H、13C NMR 光谱对 ILs 进行了表征。

  DOI：

  10.1016/j.crci.2010.04.014

文献信息

• Liquid chromatography and characterization of ether-functionalized imidazolium ionic liquids on mixed-mode reversed-phase/cation exchange stationary phase
  作者：Jeļena Leičūnaite、Igors Kļimenkovs、Jorens Kviesis、Dzintars Začs、Juris Pauls Kreišmanis

  DOI：10.1016/j.crci.2010.04.014

  日期：2010.10

  Résumé A new series [CnOmmim]Cl of imidazolium cation-based ionic liquids (ILs), with an ether functional group on the alkyl side-chain, has been prepared. The possibility of analyzing the ionic liquids by high performance liquid chromatography (HPLC) was investigated on mixed-mode reversed/cation exchange stationary phase with the aqueous-acetonitrile mobile phase. Elution parameters, such as retention factor, selectivity and column efficiency, were studied as functions of mobile phase composition and pH. The ILs were characterized by elemental analysis, and infrared, UV and 1H, 13C NMR spectroscopy.

  摘要 制备了一种新的咪唑阳离子基离子液体（ILs）系列[CnOmmim]Cl，其烷基侧链上带有一个醚官能团。研究人员采用混合模式反相/阳离子交换固定相，以水-乙腈为流动相，研究了用高效液相色谱法（HPLC）分析离子液体的可能性。研究了保留因子、选择性和柱效等洗脱参数与流动相组成和 pH 值的函数关系。通过元素分析、红外光谱、紫外光谱和 1H、13C NMR 光谱对 ILs 进行了表征。
• Preparation of Functionalized Imidazolium Salts under Microwave Irradiation
  作者：Shih‐Kang Fu、Shiuh‐Tzung Liu

  DOI：10.1080/00397910600634464

  日期：2006.6

  Abstract A direct alkylation of a substituted imidazole to prepare the corresponding functionalized ionic liquid has been developed in excellent yields under microwave irradiation.

  摘要 取代咪唑直接烷基化制备相应的功能化离子液体已在微波辐射下以优异的产率得到开发。
• 一种咪唑类次膦酸盐离子液体及其制备方法和应用
  申请人：华南理工大学

  公开号：CN118324698A

  公开（公告）日：2024-07-12

  本发明公开了一种咪唑类次膦酸盐离子液体及其制备方法和应用。本发明的咪唑类次膦酸盐离子液体由咪唑类阳离子和次膦酸盐类阴离子构成，咪唑类阳离子为#imgabs0#式中，R1为氢或甲基，R2为C1～C10的烷基、苄基、#imgabs1##imgabs2#中的一种；所述次膦酸盐类阴离子为#imgabs3#式中，R3和R4独立为乙基、C3～C5的直链烷基、异丁基、苯基中的一种。本发明的咪唑类次膦酸盐离子液体常温下为液态，与环氧树脂的相容性好，作为环氧树脂固化剂所形成的环氧树脂体系具有室温储存稳定性良好、可以在中高温下快速固化、固化物的机械性能和耐热性能优异等优点，适合进行大规模工业化应用。
• Truly solid state electrochromic devices constructed from polymeric ionic liquids as solid electrolytes and electrodes formulated by vapor phase polymerization of 3,4-ethylenedioxythiophene
  作者：Alexander S. Shaplov、Denis O. Ponkratov、Pierre-Henri Aubert、Elena I. Lozinskaya、Cédric Plesse、Ali Maziz、Petr S. Vlasov、Frédéric Vidal、Yakov S. Vygodskii

  DOI：10.1016/j.polymer.2014.04.013

  日期：2014.8

  Using polymeric ionic liquids, namely poly[1-(2-(2-(2-(methacryloyloxy)ethoxy)ethoxy)ethyl)-3-methylimidazolium]bis(trifluoromethylsulfonyl)imide or tetracyanoborate, and poly(3,4-ethylenedioxythiophene) (PEDOT) as an ion conductor and electrodes, respectively, the all-polymer-based thin-film symmetrical electrochromic devices (ECDs) have been constructed and tested. The proposed architecture serves as a prove of concept that polymeric ionic liquids (PILs) can be themselves used as solid electrolytes thus avoiding any electrolyte leakage since the ionic liquid species are grafted on the polymer backbone. Three different methods for the synthesis of PEDOT electrode films, including two new approaches consisted in vapor phase polymerization of 3,4-ethylenedioxythiophene (EDOT) in the presence of ionic monomer and poly(ethylene glycol)(di)methacrylates, have been investigated. Two oxidants, Fe[(CF3SO2)(2)N](3) and Fe[(CN)(4)B](3), bearing the same anions as PILs were prepared for the first time and utilized in the vapor phase polymerization of EDOT. It was found that the more compact structure and the highest conductivity are achieved for PEDOT electrodes prepared by vapor phase polymerization of EDOT in the presence of ionic monomer and poly(ethylene glycol)(di)methacrylates, followed by radical polymerization of the latters. The simplicity of ECDs assembly, their fast switching times (3-5 s), high coloration efficiency (up to 430 cm(2)/C), satisfactory optical contrast (up to 28.5%), absence of any liquids and good performance in air and in vacuum were found among the advantages of the proposed technology. (C) 2014 Elsevier Ltd. All rights reserved.
• STABILIZATION OF METABOLICALLY-ACTIVE CELLS IN A BLOOD SAMPLE AT AMBIENT TEMPERATURES
  申请人：Biomatrica, Inc.

  公开号：EP3155091B1

  公开（公告）日：2020-04-08