4,7-Dimethyloctan-2-on | 81060-33-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4,7-Dimethyloctan-2-on
• 英文别名: 4,7-Dimethyloctan-2-one
• CAS: 81060-33-5
• 化学式: C₁₀H₂₀O
• 分子量: 156.268
• InChiKey: IHWXNFSMZQWZHP-UHFFFAOYSA-N

物化性质

• 沸点：
  190.1±8.0 °C(Predicted)
• 密度：
  0.816±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  magnesium,2-methylbutane,bromide 、 戊-3-烯-2-酮 在 copper(I) bromide dimethylsulfide complex 、 JosiPhos 作用下， 以 various solvent(s) 为溶剂， 反应 2.0h， 生成 4,7-Dimethyloctan-2-on 、 4,7-Dimethyloctan-2-on
  参考文献：
  名称：

  铜催化对映选择性共轭加成格氏试剂到无环烯酮

  摘要：

  描述了一种高对映选择性的 Cu 催化将格氏试剂添加到无环脂肪族烯酮中。在 5 mol% 的 CuBr.SMe2 和 6 mol% 的 JosiPhos 二膦脂肪族烯酮存在下，与格氏试剂反应以提供具有高产率、区域选择性和对映选择性的 β 取代线性酮。

  DOI：

  10.1021/ja046632t

文献信息

• [EN] BENZHYDRYLATED AROMATIC SURFACTANTS<br/>[FR] TENSIOACTIFS AROMATIQUES BENZHYDRYLÉS
  申请人：INDORAMA VENTURES OXIDES LLC

  公开号：WO2020131245A1

  公开（公告）日：2020-06-25

  The present disclosure provides an alkoxylate compound containing aromatic groups in the hydrophobe allowing the compound to exhibit unique functionality, high performance and low cost, but without the toxicity and/or skin and eye irritation problems associated with conventional alkylphenol and mono-, di- and tristyrylphenol compounds.

  本公开提供了一种含有芳香基团的烷氧基化合物，使该化合物表现出独特的功能、高性能和低成本，但不会出现传统的烷基苯酚、单、二、三苯基苯酚化合物所伴随的毒性和/或皮肤和眼睛刺激问题。
• QUINOLINES AND AZA-QUINOLINES AS CRTH2 RECEPTOR MODULATORS
  申请人：Boyce Christopher W.

  公开号：US20130296300A1

  公开（公告）日：2013-11-07

  The invention provides certain quinolines and aza-quinolines of the Formula (I), and their pharmaceutically acceptable salts, wherein E, J 1 , J a , J b , R 2 , R 3 , R 22 , R a , R b , R c , R d , X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH 2 function.

  该发明提供了公式（I）中的某些喹啉和氮杂喹啉，以及它们的药学上可接受的盐，其中E、J1、Ja、Jb、R2、R3、R22、Ra、Rb、Rc、Rd、X、Y、b、n和q的定义如本文所述。该发明还提供了包含这些化合物的制药组合物，以及使用这些化合物治疗与CRTH2功能不受控制或不适当刺激相关的疾病或病症的方法。
• QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS
  申请人：Boyce Christopher W.

  公开号：US20130303517A1

  公开（公告）日：2013-11-14

  The invention provides certain quinoxalines and aza-quinoxalines of the Formula (I), and their pharmaceutically acceptable salts, wherein J 1 , J 2 , R 1 , R 2 , R 3 , R 22 , R a , R b , R c , R d , X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH 2 function.

  本发明提供了式（I）的某些喹喔啉和氮杂喹喔啉，以及其药学上可接受的盐，其中J1、J2、R1、R2、R3、R22、Ra、Rb、Rc、Rd、X、Y、b、n和q如本文所定义。本发明还提供了包含这些化合物的制药组合物，并使用这些化合物治疗与CRTH2功能不受控制或不适当刺激相关的疾病或病症的方法。
• Degreasing compositions
  申请人：Huntsman Petrochemical Corporation

  公开号：US20020111284A1

  公开（公告）日：2002-08-15

  A composition useful as a paint remover which may include a carbonate, a dibasic ester and a mono-ester. The paint stripping composition may also contain an organic sulfur-containing compound such as dimethyl sulfoxide (DMSO), a glycol ether, a ketone, or combination thereof. The composition may be used in a process for removing paint by applying it to a painted surface. A degreasing composition is also disclosed which may comprise a carbonate and a alkyl-substituted cyclo-alkane such as naphthene. The compositions have several important attributes, including low toxicity and high efficacy in removing paint and coatings.

  一种可用作脱漆剂的组合物，其中可包括碳酸盐、二元酯和单酯。脱漆组合物还可含有一种有机含硫化合物，如二甲基亚砜（DMSO）、乙二醇醚、酮或它们的组合。该组合物可用于将其涂抹在油漆表面以去除油漆的工艺中。此外，还公开了一种脱脂组合物，它可以由碳酸盐和烷基取代的环烷（如环烷）组成。这种组合物有几个重要的特性，包括毒性低和去除油漆和涂层的功效高。
• Paint and coating remover
  申请人：Huntsman Petrochemical Corporation.

  公开号：US20020142928A1

  公开（公告）日：2002-10-03

  This invention concerns a composition useful as a paint remover, comprising: alkylene carbonate such as propylene carbonate or ethylene carbonate, hydrogen peroxide, and water, and optionally an alcohol such as benzyl alcohol. In another broad respect, this invention concerns a process for removing paint, comprising: applying a composition containing alkylene carbonate, hydrogen peroxide, and water to a painted surface for a time and under conditions effective to cause blistering or bubbling of the paint. In another broad respect, this invention is a composition useful as a paint remover, comprising: dialkyl carbonate, hydrogen peroxide, and water, optionally containing an alcohol, optionally containing a glycol ether. In another broad respect, this invention is a process for removing paint, comprising: applying a composition containing dialkyl carbonate, hydrogen peroxide, and water to a painted surface for a time and under conditions effective to cause blistering or bubbling of the paint. Advantageously, the composition of this invention may include a dibasic ester (DBE).

  本发明涉及一种可用作除漆剂的组合物，其中包括：碳酸亚烷基酯（如碳酸丙烯酯或碳酸乙烯酯）、过氧化氢和水，以及可选的醇类（如苯甲醇）。从另一个广义上讲，本发明涉及一种去除油漆的工艺，包括：将含有碳酸亚烷基酯、过氧化氢和水的组合物在一定时间和有效条件下涂抹到油漆表面，使油漆起泡或起泡。从另一个大的方面来说，本发明是一种可用作油漆去除剂的组合物，其中包括：碳酸二烷基酯、过氧化氢和水，可选地含有醇，可选地含有乙二醇醚。从另一个广义上讲，本发明是一种去除油漆的工艺，包括：将含有碳酸二烷基酯、过氧化氢和水的组合物在一定时间和有效条件下涂抹在油漆表面，使油漆起泡或气泡。有利的是，本发明的组合物可以包括二盐基酯（DBE）。