1-bromo-2-n-octadecyloxybenzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-bromo-2-n-octadecyloxybenzene
• 英文别名: octadecyloxyphenyl bromide；1-bromo-2-octadecoxybenzene
• 化学式: C₂₄H₄₁BrO
• 分子量: 425.493
• InChiKey: XCMBXTIIZWGZNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.4
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-bromo-2-n-octadecyloxybenzene 在 2-双环己基膦-2',6'-二甲氧基联苯 、 palladium diacetate 、 sodium t-butanolate 、 三氯氧磷 作用下， 以 甲苯 为溶剂， 生成 4-(2-n-octadecyloxyphenyl)-1,2,3,3a,4,8b-hexahydrocyclopenta[b]indole-7-carbaldehyde
  参考文献：
  名称：

  N-(2-Alkoxyphenyl)-substituted double rhodanine indoline dyes for zinc oxide dye-sensitized solar cell

  摘要：

  The effect of N-(2-alkoxyphenyl) group in double rhodanine indoline dye on the performance of zinc oxide dye-sensitized solar cell was examined. Both J(sc) and V-oc were improved by introducing long alkoxy group due to prevention of H-aggregates formation and inhibition of electron recombination from zinc oxide surface to electrolyte. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.03.060
• 作为产物：
  描述：

  1-碘十八烷 、 2-溴苯酚 在 sodium hydroxide 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 以38%的产率得到1-bromo-2-n-octadecyloxybenzene
  参考文献：
  名称：

  N-(2-Alkoxyphenyl)-substituted double rhodanine indoline dyes for zinc oxide dye-sensitized solar cell

  摘要：

  The effect of N-(2-alkoxyphenyl) group in double rhodanine indoline dye on the performance of zinc oxide dye-sensitized solar cell was examined. Both J(sc) and V-oc were improved by introducing long alkoxy group due to prevention of H-aggregates formation and inhibition of electron recombination from zinc oxide surface to electrolyte. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.03.060

文献信息

• Process for separating and deprotecting oligonucleotides
  申请人：——

  公开号：US20040044195A1

  公开（公告）日：2004-03-04

  Methods for deprotecting and derivatizing oligonucleotides that are non-covalently bound to a solid support are described.

  本文介绍了一种去保护和衍生非共价固定在固体支持上的寡核苷酸的方法。
• PROCESS FOR SEPARATING AND DEPROTECTING OLIGONUCLEOTIDES
  申请人：Quiatech AB

  公开号：EP1546166A1

  公开（公告）日：2005-06-29
• US7345163B2
  申请人：——

  公开号：US7345163B2

  公开（公告）日：2008-03-18
• [EN] PROCESS FOR SEPARATING AND DEPROTECTING OLIGONUCLEOTIDES<br/>[FR] PROCEDE DE SEPARATION ET DE DEPROTECTION D'OLIGONUCLEOTIDES
  申请人：QUIATECH AB

  公开号：WO2004020449A1

  公开（公告）日：2004-03-11

  A method for deprotecting oligonucleotides comprising: (a) providing protected oligonucleotides wherein (i) the 5' end is linked to a hydrophobic separation function (e.g. dimethoxytrityl) or (ii) both ends are linked to a pair of hydrophobic separation functions in which pair one member is less hydrophobic than the other one (e.g. being alkyl, aryalkyl or arylsiloxyl); (b) precipitating (e.g. by drying) the oligonucleotides on a hydrophobic support (e.g. a hydrophobic polystyrene-based support) using an organic solvent, thereby non-covalently immobilizing the oligonucleotides and making them insoluble; and (c) deprotecting (i.e. removing the hydrophobic separation functions) the oligonucleotides using a reagent in an organic solvent (e.g. 2 % trichloroacetic acid in dichloromethane).