(2R,3R)-2-[3-(3,4-Dihydroxyphenyl)prop-2-enoyloxy]-3-hydroxybutanedioic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (2R,3R)-2-[3-(3,4-Dihydroxyphenyl)prop-2-enoyloxy]-3-hydroxybutanedioic acid
• 英文别名: 2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-3-hydroxybutanedioic acid
• 化学式: C₁₃H₁₂O₉
• 分子量: 312.23
• InChiKey: SWGKAHCIOQPKFW-DUXPYHPUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  162
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• USE OF CAFTARIC ACID AND LACTIC BACTERIUM IN FOOD SUPPLEMENT FOR REGULATING SKIN PIGMENTATION
  申请人：Guitard Marjorie

  公开号：US20130095074A1

  公开（公告）日：2013-04-18

  The present invention relates generally to the field of cosmetic and/or food supplement. More specifically, the present invention aims to provide the use of at least an ingredient containing caftaric acid and/or derivatives and a micro-organism and/or an enzyme capable of hydrolyzing caftaric acid and/or derivatives thereof to generate tartaric and/or caffeic acid, for improving skin tone and preventing and/or treating hyper-pigmentation of skin and/or skin color imperfections such as age-spots and other skin disorders characterized by abnormal pigments. Also, the present invention aims at providing a skin lightening agent.

  本发明通常涉及美容和/或食品补充领域。更具体地说，本发明旨在提供使用至少含有咖啡酸和/或其衍生物的成分和能够水解咖啡酸和/或其衍生物以产生酒石酸和/或咖啡酸的微生物和/或酶，以改善肤色和预防和/或治疗皮肤色素沉着和/或皮肤色泽不完美，如老年斑和其他由异常色素所特征的皮肤疾病。此外，本发明旨在提供一种皮肤美白剂。
• Composition comprising caftaric acid and/or derivatives thereof
  申请人：Nestec S.A.

  公开号：EP2210505A1

  公开（公告）日：2010-07-28

  The present invention relates generally to the field of food and drinks. In particular, for example, a composition is provided that allows to provide tartaric and/or caffeic acid to a subject. One embodiment of the present invention is a composition comprising an ingredient containing caftaric acid and/or derivatives thereof, and a micro-organism and/or an enzyme capable of hydrolysing caftaric acid and/or derivatives thereof to generate tartaric and/or caffeic acid.

  本发明一般涉及食品和饮料领域。特别是，例如，本发明提供了一种可向受试者提供酒石酸和/或咖啡酸的组合物。本发明的一个实施方案是一种组合物，包含含有酒石酸和/或其衍生物的配料，以及能够水解酒石酸和/或其衍生物以生成酒石酸和/或咖啡酸的微生物和/或酶。
• Composition comprising chicoric acid and/or derivatives thereof
  申请人：Nestec S.A.

  公开号：EP2210504A1

  公开（公告）日：2010-07-28

  The present invention relates generally to the field of food and drinks. In particular, for example, a composition is provided that allows to provide tartaric and/or caffeic acid to a subject. One embodiment of the present invention is a composition comprising an ingredient containing chicoric acid and/or derivatives thereof, and a micro-organism and/or an enzyme capable of hydrolysing chicoric acid and/or derivatives thereof to generate tartaric and/or caffeic acid.

  本发明一般涉及食品和饮料领域。特别是，例如，本发明提供了一种可向受试者提供酒石酸和/或咖啡酸的组合物。本发明的一个实施方案是一种组合物，包含含有酒石酸和/或其衍生物的成分，以及能够水解酒石酸和/或其衍生物以生成酒石酸和/或咖啡酸的微生物和/或酶。
• NATURAL BIOLOGICAL EXTRACTS OBTAINABLE BY EXTRACTION WITH EUTECTICAL SOLVENTS
  申请人：Naturex

  公开号：EP3704956A1

  公开（公告）日：2020-09-09

  A natural biological liquid extract comprising plant (e.g. vegetable) and/or animal and/or prokaryotic biological material obtained by the extraction method, wherein the method comprises the following steps: a. immersing, while stirring, a ground or unground biological material in a solvent, wherein the solvent is a clear, stable and fluid mixture comprising: (i) betaine (trimethyl glycine) or a hydrated form of betaine; (ii) at least one hydrogen bond donor compound selected from the group consisting of polyols and organic acids; and (iii) water; wherein the ratio of betaine or a hydrated form of betaine to the at least one hydrogen bond donor is from 1:1.5 to 1:3 and the proportion of water added to the mixture is from 15 to 30% by weight; with the proviso that the eutectic extraction solvent does not contain any exogenous sugar and/or amine salt and/or anion; b. macerating or percolating or infusing the mixture obtained in step a. at a temperature between 20 and 60°C; then c. filtering the extraction product obtained at b., thereby obtaining a natural biological liquid extract derived from the plant (e.g. vegetable) and/or animal and/or prokaryotic biological material.

  一种天然生物液体提取物，包括通过提取方法获得的植物（如蔬菜）和/或动物和/或原核生物材料，其中该方法包括以下步骤： a. 在搅拌的同时，将磨碎或未磨碎的生物材料浸入溶剂中，其中溶剂为透明、稳定的流体混合物，包括 (i) 甜菜碱（三甲基甘氨酸）或水合形式的甜菜碱； (ii) 至少一种选自多元醇和有机酸的氢键供体化合物；以及 (iii) 水； 其中甜菜碱或甜菜碱的水合形式与至少一种氢键供体的比例为 1:1.5 至 1:3，加入混合物中的水的比例为 15%至 30%（按重量计）； 但共晶萃取溶剂不含任何外源糖和/或胺盐和/或阴离子； b. 将步骤 a 中得到的混合物在 20 至 60°C 的温度下浸渍、渗滤或灌注；然后 c. 过滤 b.步骤中得到的提取物，从而得到从植物（如蔬菜）和/或动物和/或原核生物材料中提取的天然生物液体提取物。
• Glycan therapeutics and related methods thereof
  申请人：KALEIDO BIOSCIENCES, INC.

  公开号：US10314853B2

  公开（公告）日：2019-06-11

  Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

  本发明提供了可选择包含微量营养素、多酚、益生元、益生菌或其他制剂的聚糖疗法制剂、药物组合物及其医用食品，以及制造方法。还提供了使用所述糖治疗剂的方法，例如用于调节人类胃肠道微生物群和治疗菌群失调。

表征谱图