4-[4-[(E)-2-(3,5-dimethoxy-4-octanoyloxyphenyl)ethenyl]quinolin-1-ium-1-yl]butanoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-[4-[(E)-2-(3,5-dimethoxy-4-octanoyloxyphenyl)ethenyl]quinolin-1-ium-1-yl]butanoic acid
• 化学式: C31H38NO6+
• 分子量: 520.6
• InChiKey: YHRYMQGYTBMXCK-WUKNDPDISA-O

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  38
• 可旋转键数：
  16
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  85.9
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• PROCEDE ET MILIEU DE DETECTION/IDENTIFICATION DE MICROORGANISMES A ACTIVITE ESTERASE ET/OU OSIDASE ET/OU PEPTIDASE ET/OU SULFATASE ET/OU PHOSPHATATE
  申请人：BIO MERIEUX

  公开号：EP1334206B1

  公开（公告）日：2006-05-24
• Method and medium for the detecting/identifying microorganisms with esterase and/or r osidase and/or peptidase and/or sulfatase and/or phosphatase activity
  申请人：Gilbert Sandra

  公开号：US20050014215A1

  公开（公告）日：2005-01-20

  The invention relates to a medium for biological analysis by biochemical means involving chromogenic or fluorogenic substrates that react with enzymes (esterases and/or osidases and/or peptidases and/or sulfatases and/or phosphatases) specific for the target strains. The object of the invention is to improve the sensitivity, initial translucence, stability and ease of use of such identification/detection media. This object is achieved by the medium according to the invention, which is in a stable, ready-to-use liquid or gel form and contains at least one emulsifying stabilizer of the fatty acid sorbitan ester/fatty acid type and at least one solvent (dimethyl sulfoxide). This medium is obtained by mixing a stock solution of esterase and/or osidase and/or peptidase and/or sulfatase and/or phosphatase substrates in the solvent, and the emulsifying stabilizer, with some of the constituents of the culture medium. The invention further relates to the preparation of such a medium and to the use of a fatty acid sorbitan ester/fatty acids as an emulsifying stabilizer in a medium for the detection/identification of microorganisms, especially bacteria or yeasts, with esterase and/or osidase and/or peptidase and/or sulfatase and/or phosphatase activities.
• US7217536B2
  申请人：——

  公开号：US7217536B2

  公开（公告）日：2007-05-15
• [EN] CHROMOGENIC SUBSTRATES FOR THE DETECTION OF SALMONELLA<br/>[FR] SUBSTRATS CHROMOGENES DE DETECTION DE Salmonella
  申请人：PRAILL PRICE RICHARDSON LTD.

  公开号：WO1999041409A1

  公开（公告）日：1999-08-19

  (EN) The invention relates to a method of detecting $i(salmonella) spp, comprising exposing a sample to a substrate containing a chromogenic compound that reacts with a cellular esterase/lipase present in $i(salmonella) spp and having an affinity for octanoate esters, the chromogenic compound comprising a 4-[2-(4-octanoyloxy-3,5-dimethoxyphenyl)-vinyl]-quinolinium-1-(propan-3-ylcarboxylic acid) cation and an anion. The invention further provides chromogenic compounds and media for such methods.(FR) L'invention concerne une méthode de détection de $i(Salmonella) spp., la méthode consistant à exposer un substrat contenant un composé chromogène entrant en réaction avec une estérase/lipase cellulaire présente dans $i(Salmonella) spp. et présentant une affinité avec des esters d'octanoate, le composé chromogène comprenant un cation 4-[2-(4-octanoyloxy-3,5-diméthoxyphényl)-vinyl]-quinolinium-1-(propan-3-yl acide carboxylique) et un anion. L'invention concerne également des composés chromogènes et des milieux d'application de ces méthodes.