[(1R,3R,5R,6R,8R,10R,11R,13R,15R,16R,18R,20R,21R,23R,25R,26R,28R,30R,31R,33R,35R,36R,38R,40R,41S,42R,43S,44R,45S,46R,47S,48R,49S,50R,51S,52R,53S,54R,55S,56R)-40-(hydroxymethyl)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecamethoxy-5,10,15,20,25,35-hexakis(methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontan-30-yl]methanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(1R,3R,5R,6R,8R,10R,11R,13R,15R,16R,18R,20R,21R,23R,25R,26R,28R,30R,31R,33R,35R,36R,38R,40R,41S,42R,43S,44R,45S,46R,47S,48R,49S,50R,51S,52R,53S,54R,55S,56R)-40-(hydroxymethyl)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecamethoxy-5,10,15,20,25,35-hexakis(methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontan-30-yl]methanol
• 化学式: C₇₀H₁₂₄O₄₀
• 分子量: 1605.73
• InChiKey: MIAVJCJYEAJCRW-QZJCFOGDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.4
• 重原子数：
  110
• 可旋转键数：
  30
• 环数：
  30.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  391
• 氢给体数：
  2
• 氢受体数：
  40

反应信息

• 作为反应物：
  描述：

  甲基磺酰氯 、 [(1R,3R,5R,6R,8R,10R,11R,13R,15R,16R,18R,20R,21R,23R,25R,26R,28R,30R,31R,33R,35R,36R,38R,40R,41S,42R,43S,44R,45S,46R,47S,48R,49S,50R,51S,52R,53S,54R,55S,56R)-40-(hydroxymethyl)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecamethoxy-5,10,15,20,25,35-hexakis(methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontan-30-yl]methanol 在 吡啶 作用下， 生成 6¹,6³-di-O-methylsulfonyl-cyclomalto-octaose permethylate
  参考文献：
  名称：

  制备二-O-三苯基甲基-（三苯甲基-）环麦芽糖酶，并通过“六角五糖降解”四个位置异构体进行分离和表征。

  摘要：

  环麦芽八糖（1，cG8）的四种区域异构二三苯甲基化衍生物，即6（I），6（n）-di-O-三苯甲基-cG8S，是通过1与氯三苯甲烷在吡啶中反应制备的，并通过高效液相色谱。通过“六-戊糖降解”，然后通过快速原子轰击质谱法检查产物，实现了对四个二三苯甲基取代的衍生物的区域化学测定。

  DOI：

  10.1248/cpb.41.866
• 作为产物：
  描述：

  6¹,6³-di-O-trityl-cyclomalto-octaose permethylate 在 溶剂黄146 作用下， 反应 1.0h， 生成 [(1R,3R,5R,6R,8R,10R,11R,13R,15R,16R,18R,20R,21R,23R,25R,26R,28R,30R,31R,33R,35R,36R,38R,40R,41S,42R,43S,44R,45S,46R,47S,48R,49S,50R,51S,52R,53S,54R,55S,56R)-40-(hydroxymethyl)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecamethoxy-5,10,15,20,25,35-hexakis(methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontan-30-yl]methanol
  参考文献：
  名称：

  制备二-O-三苯基甲基-（三苯甲基-）环麦芽糖酶，并通过“六角五糖降解”四个位置异构体进行分离和表征。

  摘要：

  环麦芽八糖（1，cG8）的四种区域异构二三苯甲基化衍生物，即6（I），6（n）-di-O-三苯甲基-cG8S，是通过1与氯三苯甲烷在吡啶中反应制备的，并通过高效液相色谱。通过“六-戊糖降解”，然后通过快速原子轰击质谱法检查产物，实现了对四个二三苯甲基取代的衍生物的区域化学测定。

  DOI：

  10.1248/cpb.41.866

文献信息

• Preparation of Di-O-triphenylmethyl-(trityl-)cyclomalto-octaoses, and Isolation and Characterization by "Hex-5-enose Degradation" of Four Positional Isomers.
  作者：Toshiko TANIMOTO、Tomoko SAKAKI、Kyoko KOIZUMI

  DOI：10.1248/cpb.41.866

  日期：——

  The regiochemical determination of the four ditrityl-substituted derivatives has been achieved by means of the "hex-5-enose degradation," followed by examination of the products by fast-atom bombardment-mass spectrometry.

  环麦芽八糖（1，cG8）的四种区域异构二三苯甲基化衍生物，即6（I），6（n）-di-O-三苯甲基-cG8S，是通过1与氯三苯甲烷在吡啶中反应制备的，并通过高效液相色谱。通过“六-戊糖降解”，然后通过快速原子轰击质谱法检查产物，实现了对四个二三苯甲基取代的衍生物的区域化学测定。