2,2,8-trimethyl-1,7-dioxaspiro[5.5]undecane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2,8-trimethyl-1,7-dioxaspiro[5.5]undecane
• 英文别名: 2,2,8-Trimethyl-1,7-dioxaspiro[5.5]undecane
• 化学式: C₁₂H₂₂O₂
• 分子量: 198.305
• InChiKey: YYHUMKLNIINDOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-甲基-4-戊炔-2-醇 在 正丁基锂 、 对甲苯磺酸 作用下， 反应 4.0h， 生成 2,2,8-trimethyl-1,7-dioxaspiro[5.5]undecane
  参考文献：
  名称：

  Synthesis and absolute stereochemistry of spiroacetals in rove beetles (Coleoptera: Staphylinidae)

  摘要：

  The unusual branched-carbon chain spiroacetal, 2,2,8-trimethyl-1,7-dioxaspiro[5.5]undecane, has been synthesised as its racemate and (6S,8R)-isomer. The natural compound, identified in the rove beetle, Ontholestes murinus (L.) proved to be the (6R,8S)-isomer. (E,E)-2,8-Dimethyl-1,7-dioxaspiro[5.5]undecane, a major component of the volatiles from the same insect, is the (2S,6R,8S)-isomer, but is largely racemic in Ontholestes tesselatus (Geoffr. Fourcr.). (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01612-3

文献信息

• SLOW-RELEASE FORMULATION CONTAINING GEL COMPOSITION FOR USE ON PESTS
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP2805615A1

  公开（公告）日：2014-11-26

  Provided is a sustained release preparation comprising an insect pest-targeting gel composition, the preparation being free from leakage or reaction of a volatile substance and being capable of releasing the volatile substance at a constant rate. More specifically, provided is a sustained release preparation comprising a polymer tube and an insect pest-targeting gel composition in the polymer tube, the composition comprising one or more volatile substances and an oil gelling agent, wherein the volatile substances are comprised in an amount of from 70.0 to 99.0% by weight by the insect pest-targeting composition and are released outside of the polymer tube through the polymer tube.

  本发明提供了一种包含害虫靶向凝胶组合物的缓释制剂，该制剂中的挥发性物质不会泄漏或发生反应，并且能够以恒定的速率释放挥发性物质。更具体地说，本发明提供了一种持续释放制剂，包括聚合物管和聚合物管中的害虫靶向凝胶组合物，该组合物包括一种或多种挥发性物质和油胶凝剂，其中挥发性物质的含量为害虫靶向组合物重量的 70.0% 至 99.0%，并通过聚合物管释放到聚合物管外。
• Insect pest-targeting gel composition and sustained release preparation comprising that
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US10244750B2

  公开（公告）日：2019-04-02

  Provided are an insect pest-targeting gel composition causing neither leakage nor reaction of a volatile substance and capable of releasing the volatile substance at a constant rate; and a sustained release preparation including the insect pest-targeting gel composition. More specifically, provided is an insect pest-targeting gel composition including one or more volatile substances and an oil gelling agent, wherein the volatile substance is included in an amount of from 70.0 to 99.0% by weight by the insect pest-targeting gel composition.

  本发明提供了一种害虫靶向凝胶组合物，该组合物不会导致挥发性物质泄漏或反应，并能以恒定速率释放挥发性物质；还提供了一种包含该害虫靶向凝胶组合物的缓释制剂。更具体地说，提供了一种包含一种或多种挥发性物质和油胶凝剂的害虫靶向凝胶组合物，其中挥发性物质的含量为害虫靶向凝胶组合物重量的 70.0% 至 99.0%。
• GEL COMPOSITION AGAINST HARMFUL INSECTS, AND SUSTAINED-RELEASE PREPARATION HAVING SAID GEL COMPOSITION INTRODUCED THEREIN
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP2789236B1

  公开（公告）日：2020-09-30
• SUSTAINED RELEASE PREPARATION COMPRISING INSECT PEST-TARGETING GEL COMPOSITION
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20140308328A1

  公开（公告）日：2014-10-16

  Provided is a sustained release preparation comprising an insect pest-targeting gel composition, the preparation being free from leakage or reaction of a volatile substance and being capable of releasing the volatile substance at a constant rate. More specifically, provided is a sustained release preparation including a polymer tube having a sharp end and an insect pest-targeting gel composition in the polymer tube, the composition including one or more volatile substances and an oil gelling agent, wherein the volatile substances are included in an amount of from 70.0 to 99.0% by weight by the insect pest-targeting composition and are released outside of the polymer tube through the polymer tube.
• INSECT PEST-TARGETING GEL COMPOSITION AND SUSTAINED RELEASE PREPARATION COMPRISING THAT
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20140357707A1

  公开（公告）日：2014-12-04

  Provided are an insect pest-targeting gel composition causing neither leakage nor reaction of a volatile substance and capable of releasing the volatile substance at a constant rate; and a sustained release preparation including the insect pest-targeting gel composition. More specifically, provided is an insect pest-targeting gel composition including one or more volatile substances and an oil gelling agent, wherein the volatile substance is included in an amount of from 70.0 to 99.0% by weight by the insect pest-targeting gel composition.