2-ethylhexyl (E)-3-(p-tolyl)acrylate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 2-ethylhexyl (E)-3-(p-tolyl)acrylate
• 英文别名: 2-ethylhexyl p-methylcinnamate；2-ethylhexyl (E)-3-(4-methylphenyl)prop-2-enoate
• 化学式: C₁₈H₂₆O₂
• 分子量: 274.403
• InChiKey: IOKMUTHFFKJQRY-OUKQBFOZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  丙烯酸2-乙基己酯 、 对氯甲苯 在 (1,3-dimesitylimidazol-2-ylidene)(naphthoquinone)palladium sodium acetate 作用下， 以 various solvent(s) 为溶剂， 反应 48.0h， 以32%的产率得到2-ethylhexyl (E)-3-(p-tolyl)acrylate
  参考文献：
  名称：

  New Palladium Carbene Catalysts for the Heck Reaction of Aryl Chlorides in Ionic Liquids

  摘要：

  [GRAPHICS]The Heck reaction of aryl chlorides was investigated in the presence of defined monocarbenepalladium(0) complexes. Activated and nonactivated aryl chlorides provide the corresponding cinnamic esters and stilbenes in (Bu4NBr)-Bu-n as a ionic liquid in good to excellent yields.

  DOI：

  10.1021/ol020103h

文献信息

• [EN] METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND<br/>[FR] PROCÉDÉ DE COUPLAGE D'UN PREMIER COMPOSÉ À UN SECOND COMPOSÉ
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2016057771A1

  公开（公告）日：2016-04-14

  The present disclosure describes a method of coupling a first compound to a second compound, the method comprising: providing the first compound having a fluorosulfonate substituent; providing the second compound comprising an alkene; and reacting the first compound and the second compound in a reaction mixture, the reaction mixture including a catalyst having at least one group 10 atom, the reaction mixture under conditions effective to couple the first compound to the second compound.

  本公开说明书描述了一种将第一化合物耦合到第二化合物的方法，该方法包括：提供具有氟磺酸酯取代基的第一化合物；提供包含烯烃的第二化合物；并在反应混合物中反应第一化合物和第二化合物，反应混合物包括至少一个10族元素的催化剂，在有效条件下将第一化合物耦合到第二化合物。
• SKIN-LIGHTENING AGENT CONTAINING EQUOL COMPOUND AS ACTIVE INGREDIENT
  申请人：Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo

  公开号：EP2145615A1

  公开（公告）日：2010-01-20

  An object of the present invention is to provide a whitening agent containing a novel whitening substance as an effective ingredient. The above object is attained by providing a whitening agent containing equol and/or equol glycoside, in which one or more glycosyl groups bind to the hydroxyl group(s) of equol, as an effective ingredient.

  本发明的目的是提供一种含有新型增白物质作为有效成分的增白剂。为达到上述目的，本发明提供了一种美白剂，其有效成分含有马郁兰和/或马郁兰糖苷，其中一个或多个糖基与马郁兰的羟基结合。
• Ehrentraut; Zapf; Beller, Synlett, 2000, # 11, p. 1589 - 1592
  作者：Ehrentraut、Zapf、Beller

  DOI：——

  日期：——
• A highly active phosphine-free catalyst system for Heck reactions of aryl bromides
  作者：Manfred T. Reetz、Elke Westermann、Renate Lohmer、Gunther Lohmer

  DOI：10.1016/s0040-4039(98)01967-4

  日期：1998.11

  Palladium salts such as Pd(OAc)(2) or PdCl2(PhCN)(2) in the presence of N,N-dimethylglycine (DMG) constitute the simplest and one of the most reactive and selective catalyst systems for the Heck reaction of aryl bromides with olefins known to date. (C) 1998 Elsevier Science Ltd. All rights reserved.
• 4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME
  申请人：CELGENE CORPORATION

  公开号：EP2142534A2

  公开（公告）日：2010-01-13