piloside A

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: piloside A
• 英文别名: [2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl 2,6-dimethoxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoate
• 化学式: C₂₈H₃₆O₁₆
• 分子量: 628.584
• InChiKey: JWHWZZKHHKKLBO-ABSLVDNQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  44
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  244
• 氢给体数：
  8
• 氢受体数：
  16

反应信息

• 作为反应物：
  描述：

  piloside A 在 β-glucosidase 作用下， 以 acetate buffer 为溶剂， 反应 96.0h， 以21 mg的产率得到2,6-dimethoxy-3-hydroxybenzoic acid
  参考文献：
  名称：

  Benzylbenzoate and norlignan glucosides from Curculigo pilosa: structural analysis and in vitro vascular activity

  摘要：

  From the rhizomes of Curculigo pilosa, two benzylbenzoate diglucosides, piloside A and piloside B, and a glucosyl-fused norlignan, pilosidine, previously obtained only as the tetra-O-methyl derivative, were isolated. Pilosidine showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(00)00256-9

文献信息

• Benzylbenzoate and norlignan glucosides from Curculigo pilosa: structural analysis and in vitro vascular activity
  作者：Giovanna Palazzino、Corrado Galeffi、Elena Federici、Franco Delle Monache、Maria Francesca Cometa、Maura Palmery

  DOI：10.1016/s0031-9422(00)00256-9

  日期：2000.11

  From the rhizomes of Curculigo pilosa, two benzylbenzoate diglucosides, piloside A and piloside B, and a glucosyl-fused norlignan, pilosidine, previously obtained only as the tetra-O-methyl derivative, were isolated. Pilosidine showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations. (C) 2000 Elsevier Science Ltd. All rights reserved.