(2R,3S,4R,5R)-2,3,4,5-四羟基-1-氧代己烷-1-磺酸 | 3458-06-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: (2R,3S,4R,5R)-2,3,4,5-四羟基-1-氧代己烷-1-磺酸
• 英文名称: 6-Sulfo-chinovose
• 英文别名: 6-Sulfo-D-chinovose；6-sulfo-6-deoxy-D-glucose；L_r-2c_F,4t_F,5r_F-Tetrahydroxy-6-oxo-hexan-1-sulfonsaeure；6-Sulfo-6-desoxy-D-glucose；D-Glucose, 6-deoxy-6-sulfo-；(2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexane-1-sulfonic acid
• CAS: 3458-06-8
• 化学式: C₆H₁₂O₈S
• 分子量: 244.222
• InChiKey: FHHZLHYDSYNQDK-SLPGGIOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  161
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  6-deoxy-1,2-O-isopropylidene-6-(4'-methylbenzene)sulfonyloxy-D-glucofuranose 在 sodium sulfite 作用下， 以 乙醇 为溶剂， 生成 (2R,3S,4R,5R)-2,3,4,5-四羟基-1-氧代己烷-1-磺酸
  参考文献：
  名称：

  The Plant Sulfolipid. VII. Synthesis of 6-Sulfo-α-D-quinovopyranosyl-(1→1″)-glycerol and Radiochemical Syntheses of Sulfolipids

  摘要：

  DOI：

  10.1021/ja00860a015

文献信息

• COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND SUBSEQUENT MODIFICATION OF URIDINE-5'-DIPHOSPHOSULFOQUINOVOSE (UDP-SQ)
  申请人：MICHIGAN STATE UNIVERSITY

  公开号：EP1356072A2

  公开（公告）日：2003-10-29
• Compositions and methods for the synthesis and subsequent modification of uridine-5'-diphosphosulfoquinovose (UDP-SQ)
  申请人：Benning Christoph

  公开号：US20070134778A1

  公开（公告）日：2007-06-14

  The present invention is directed to compositions and methods related to the synthesis and modification of uridine-5′-diphospho-sulfoquinovose (UDP-SQ). In particular, the methods of the present invention comprise the utilization of recombinant enzymes from Arabidopsis thaliana , UDP-glucose, and a sulfur donor to synthesize UDP-SQ, and the subsequent modification of UDP-SQ to form compounds including, but not limited to, 6-sulfo-α-D-quinovosyl diaclyglycerol (SQDG) and alkyl sulfoquinovoside. The compositions and methods of the invention provide a more simple, rapid means of synthesizing UDP-SQ, and the subsequent modification of UDP-SQ to compounds including, but not limited to, SQDG.
• US7226764B1
  申请人：——

  公开号：US7226764B1

  公开（公告）日：2007-06-05
• US7479387B2
  申请人：——

  公开号：US7479387B2

  公开（公告）日：2009-01-20
• [EN] COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND SUBSEQUENT MODIFICATION OF URIDINE-5'-DIPHOSPHOSULFOQUINOVOSE (UDP-SQ)<br/>[FR] COMPOSITIONS ET PROCEDES PERMETTANT LA SYNTHESE ET LA MODIFICATION SUBSEQUENTE D'URIDINE-5'-DIPHOSPHOSULFOQUINOVOSE (UDP-SQ)
  申请人：UNIV MICHIGAN STATE

  公开号：WO2002048706A2

  公开（公告）日：2002-06-20

  The present invention is directed to composition and methods related to the synthesis and modification of uridine-5'-diphospho-sulfoquinovose (UDP-SQ).In particular, the methods of the present invention comprise the utilization of recombinant enzymes from Arabidopsis thaliana, UDP-glucose, and a sulfur donor to synthesize UDP-SQ, and the subsequent modification of UDP-SQ to form compounds inlcuding, but not limited to, 6-sulfo-a-D-quinovosyl diaclyglycerol (SQDG) and alkyl sulfoquinovoside. The compositions and methods of the invention provide a more simple, rapid means of synthesizing UDP-SQ, and the subsequent modification of UDP-SQ to compounds including, but not limited to, SQDG.