己烷-2,3,4,5-四醇 | 25289-20-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 己烷-2,3,4,5-四醇
• 英文名称: hexane-2,3,4,5-tetraol
• 英文别名: Hexan-2,3,4,5-tetraol；hexane-2,3,4,5-tetrol
• CAS: 25289-20-7
• 化学式: C₆H₁₄O₄
• 分子量: 150.175
• InChiKey: TZQPAZWGRJYTLN-UHFFFAOYSA-N

物化性质

• 沸点：
  358.2±37.0 °C(Predicted)
• 密度：
  1.260±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 四氧化锇 、 水 、 双氧水 作用下， 生成 己烷-2,3,4,5-四醇
  参考文献：
  名称：

  Reppe,W., Acetylene Chemistry S. 109

  摘要：

  DOI：

文献信息

• Chemically patterned hydrogels, manufacture and use thereof
  申请人：Shoichet Molly

  公开号：US20080286360A1

  公开（公告）日：2008-11-20

  A chemically patterned modified hydrogel formed from a modified hydrogel is provided. The hydrogel is conjugated with a multiphoton photocleavable molecule. The molecule has a multiphoton-labile protective group and a protected group. The protective group is cleavable upon multiphoton excitation to deprotect the protected group, without substantial polymerization of the hydrogel. The chemically patterned modified hydrogel is formed by exposing the modified hydrogel to multiphoton excitation to deprotect a portion of the protected groups.

  提供了一种化学图案化的改性水凝胶，该水凝胶由改性水凝胶形成。水凝胶与多光子光可裂解分子偶联。该分子具有多光子敏感保护基团和受保护基团。保护基团在多光子激发下可裂解，以解除对受保护基团的保护，而不会显著聚合水凝胶。通过将改性水凝胶暴露于多光子激发以解除部分受保护基团的保护，形成化学图案化的改性水凝胶。
• Production process for hydroxyalkyl (meth) acrylate
  申请人：Nippon Shokubai Co., Ltd.

  公开号：US20040030180A1

  公开（公告）日：2004-02-12

  There is disclosed a novel production process for a hydroxyalkyl (meth)acrylate in which: the diffusion of harmful substances due to disposal of catalysts can be reduced; and also the amount of the catalyst as used can be greatly saved in the entire production process. This production process comprises the step of carrying out a reaction between (meth)acrylic acid and an alkylene oxide in the presence of a catalyst in order to produce the hydroxyalkyl (meth)acrylate; with the production process being characterized by further comprising the step of recovering the catalyst as has been used for the reaction.

  揭示了一种新型的羟基烷基（甲基）丙烯酸酯的生产工艺，其中：可以减少由于催化剂废弃而导致有害物质的扩散；同时在整个生产过程中也可以大大节省所使用的催化剂量。该生产工艺包括在催化剂存在下进行丙烯酸和烷基氧化物之间的反应，以生产羟基烷基（甲基）丙烯酸酯；该生产工艺的特点是进一步包括回收已用于反应的催化剂的步骤。
• [EN] METHANOL PRODUCTION PROCESS<br/>[FR] PROCÉDÉ DE PRODUCTION DE MÉTHANOL
  申请人：ISIS INNOVATION

  公开号：WO2009130452A1

  公开（公告）日：2009-10-29

  The invention provides a process for producing methanol, which process comprises treating a compound which is: a sugar alcohol of formula (I) in which n is 0 or an integer equal to or greater than 1, or a sugar of formula (II) in which m is an integer equal to or greater than 1, with hydrogen in the presence of a hydrogenolysis catalyst comprising a transition metal, and thereby producing said methanol by hydrogenolysis of said compound.

  该发明提供了一种生产甲醇的过程，该过程包括处理以下化合物：具有式(I)的糖醇，其中n为0或大于等于1的整数，或具有式(II)的糖，其中m为大于等于1的整数，在氢气存在下与过渡金属组成的氢解催化剂反应，从而通过对该化合物进行氢解来生产所述的甲醇。
• Fredericamycin Derivatives
  申请人：Simon Werner

  公开号：US20080318942A1

  公开（公告）日：2008-12-25

  The invention relates to new fredericamycin derivatives, to pharmaceutical drugs containing them or their salts, and to the use of the fredericamycin derivatives for the treatment of diseases, especially tumor diseases.

  该发明涉及新的弗雷德霉素衍生物，以及含有它们或它们的盐的药物制剂，以及利用弗雷德霉素衍生物治疗疾病，特别是肿瘤疾病的用途。
• BENZAMIDE mGluR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME
  申请人：Conn P. Jeffrey

  公开号：US20090042855A1

  公开（公告）日：2009-02-12

  In one aspect, the invention relates to compounds, including phenylethynylbenzamide derivatives, cycloalkylethynylbenzamide derivatives, styrylbenzamide derivatives, 4-(3-phenyl-1,2,4-oxadiazol-5-yl)benzamide derivatives, 4-(pyridinylethynyl)benzamide derivatives, and N 1 -phenylterephthalamide derivatives, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本发明涉及化合物，包括苯乙炔基苯甲酰胺衍生物、环烷基乙炔基苯甲酰胺衍生物、苯乙烯基苯甲酰胺衍生物、4-(3-苯基-1,2,4-噁唑-5-基)苯甲酰胺衍生物、4-(吡啶乙炔基)苯甲酰胺衍生物和N1-苯基对苯二甲酰胺衍生物，它们是代谢型谷氨酸受体亚型5 (mGluR5) 的正向变构调节剂；制备这些化合物的合成方法；含有这些化合物的药物组合物；以及使用这些化合物和组合物治疗与谷氨酸功能失调相关的神经和精神障碍的方法。本摘要旨在作为搜索特定领域的扫描工具，不限制本发明。