(3aS,4S,6R,6aS)-6-[(4R)-2,2-二甲基-1,3-二氧戊环-4-基]-N-羟基-2,2-二甲基四氢呋喃并[3,4-d][1,3]二氧杂环戊烯-4-胺 | 35023-80-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: (3aS,4S,6R,6aS)-6-[(4R)-2,2-二甲基-1,3-二氧戊环-4-基]-N-羟基-2,2-二甲基四氢呋喃并[3,4-d][1,3]二氧杂环戊烯-4-胺
• 中文别名: 二丙酮甘露糖肟
• 英文名称: (2,2-dimethyl-1,3-dioxolan-4-yl)-[5-[(Z)-hydroxyiminomethyl]-2,2-dimethyl-1,3-dioxolan-4-yl]methanol
• CAS: 35023-80-4；104012-85-3；104320-20-9；129312-24-9；129312-25-0；129312-26-1；129312-27-2；129312-29-4；129312-30-7
• 化学式: C₁₂H₂₁NO₆
• 分子量: 275.302
• InChiKey: GCYSHDWLKNPSBV-ACAGNQJTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  89.7
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• METHOD FOR THE GENERATION OF CHEMICAL LIBRARIES
  申请人：ETH ZURICH

  公开号：US20170088878A1

  公开（公告）日：2017-03-30

  A method for the generation of oligomers or a mixture of oligomers to form a chemical library by amide-forming oligomerization comprises the steps of 1) reacting a mixture of at initiator (I) with monomer (M) to form a dimer of the initiator (I) and the monomer (M) or a pre-oligomer with an initiator (I) attached to a chain of more than one monomer (M) or a mixture thereof by amide-bond formation; 2) optionally adding at least one terminator (T) for the formation of a linear oligomer or a mixture of linear oligomers by amide-bond formation; or, for the formation of a cyclic oligomer or a mixture of cyclic oligomers by amide-bond formation, changing the reaction conditions relative to step 1) so as to form a linking covalent bond between the at least one initiator (I).
• [EN] METHOD FOR THE GENERATION OF CHEMICAL LIBRARIES<br/>[FR] PROCÉDÉ DE GÉNÉRATION DE BANQUES CHIMIQUES
  申请人：ETH ZUERICH

  公开号：WO2015124443A1

  公开（公告）日：2015-08-27

  A method for the generation of oligomers or a mixture of oligomers to form a chemical library by amide-forming oligomerization comprises the steps of ) reacting a mixture of at least one initiator (I) with at least one monomer (M) to form a dimer of the initiator (I) and the monomer (M) or a pre-oligomer with an initiator (I) attached to a chain of more than one monomer (M) or a mixture thereof by amide-bond formation; 2) optionally adding at least one terminator (T) for the formation of a linear oligomer or a mixture of linear oligomers by amide-bond formation; or, for the formation of a cyclic oligomer or a mixture of cyclic oligomers by amide-bond formation, changing the reaction conditions relative to step 1) so as to form a linking covalent bond between the at least one initiator (I) and preferably the respective terminal monomer (M) of the dimer or pre-oligomer formed in step 1).