5H-phenanthridin-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 5H-phenanthridin-3-one
• 化学式: C₁₃H₉NO
• 分子量: 195.22
• InChiKey: HHVKHNGREKVKGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427B1

  公开（公告）日：1989-07-05
• BENZO(C)QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS
  申请人：Applied Research Systems ARS Holding N.V.

  公开号：EP1066284B1

  公开（公告）日：2005-08-31
• METHOD AND COMPOSITIONS FOR TREATING 5ALPHA-REDUCTASE TYPE 1 AND TYPE 2 DEPENDENT CONDITIONS
  申请人：Dyad Pharmaceutical Corporation

  公开号：EP1689864A2

  公开（公告）日：2006-08-16
• Methods and Compositions for Treating 5Alpha-Reductase Type 1 and Type 2 Dependent Conditions
  申请人：Hoke Glenn D.

  公开号：US20080207545A1

  公开（公告）日：2008-08-28

  The invention relates generally to the use of anti-sense oligonucleotides, small interfering RNA, and ribozymes to modulate expression of the human steroid 5α-reductase gene and thereby modulate levels of dihydrotestosterone (DHT). Elevated levels of DHT are associated with various disorders including, but not limited to, skin diseases, hair loss, hirsuitism, and benign prostatic hyperplasia. The invention specifically relates to formulations of these anti-sense oligonucleotides, small interfering RNA, and ribozymes for administration to treat and prevent disorders
• US5621104A
  申请人：——

  公开号：US5621104A

  公开（公告）日：1997-04-15