[(10-Methylacridin-9-ylidene)-phenylsulfanylmethyl] dihydrogen phosphate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: [(10-Methylacridin-9-ylidene)-phenylsulfanylmethyl] dihydrogen phosphate
• 化学式: C₂₁H₁₈NO₄PS
• 分子量: 411.4
• InChiKey: IUCHWSAIHYGPIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  95.3
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• ELECTROCHEMILUMINESCENCE FROM ACRIDAN COMPOUNDS
  申请人：Akhavan-Tafti Hashen

  公开号：US20070059841A1

  公开（公告）日：2007-03-15

  Methods are disclosed for producing electrochemiluminescence by electrochemically oxidizing an acridan compound at an electrode in the presence of a peroxide. Maintaining a sufficiently positive potential results in continuous oxidation of the acridan compound to an acridinium compound which reacts with peroxide to produce the luminescence. Light emission can be reversibly and repeatedly cycled on and off by sweeping the potential between two values. The acridan compounds can be provided with a labeling group for linking to an analyte or analyte binding partner. The present electrochemiluminescent reaction can find use in assay methods for detecting analytes by immunoassays and nucleic acid assays.
• Assay Methods Using Chemiluminescent Detection of Peroxidase
  申请人：Akhavan-Tafti Hashem

  公开号：US20090246819A1

  公开（公告）日：2009-10-01

  Methods for generating chemiluminescence rapidly by reaction of at least one compound comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups with a peroxidase enzyme and a peroxide are disclosed. The chemiluminescence thus produced can be used as a detectable signal in assays for peroxidase enzymes or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs. Use of the methods provides rapid signal generation, achieving a plateau intensity in under one minute. The substrate can be provided in a composition which demonstrates unexpectedly long storage stability.
• US7186568B1
  申请人：——

  公开号：US7186568B1

  公开（公告）日：2007-03-06
• US7247726B2
  申请人：——

  公开号：US7247726B2

  公开（公告）日：2007-07-24
• US7560556B2
  申请人：——

  公开号：US7560556B2

  公开（公告）日：2009-07-14