7-methoxy-2-N-methyl-2-N,4-N-bis(2-phenylethyl)quinoline-2,4-diamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7-methoxy-2-N-methyl-2-N,4-N-bis(2-phenylethyl)quinoline-2,4-diamine
• 化学式: C₂₇H₂₉N₃O
• 分子量: 411.5
• InChiKey: GSBOBKBWUSQYKT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  31
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  37.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS
  申请人：PureTech LYT, Inc.

  公开号：US20220001015A1

  公开（公告）日：2022-01-06

  The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.