(RS)-4-羧基-3-羟基苯甘氨酸 | 134052-66-7

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 甘氨酸类衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (RS)-4-羧基-3-羟基苯甘氨酸
• 英文名称: (RS)-4-Carboxy-3-hydroxyphenylglycine
• 英文别名: 4-[amino(carboxy)methyl]-2-hydroxybenzoic acid
• CAS: 134052-66-7
• 化学式: C₉H₉NO₅
• 分子量: 211.17
• InChiKey: GXZSAQLJWLCLOX-UHFFFAOYSA-N

物化性质

• 沸点：
  479.1±45.0 °C(Predicted)
• 密度：
  1.596±0.06 g/cm3(Predicted)
• 溶解度：
  1eq 中可溶解至 100 毫升氢氧化钠

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  121
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
  申请人：Kõster Hubert

  公开号：US20100248264A1

  公开（公告）日：2010-09-30

  Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for analyzing complex protein mixtures, such as the proteome. The compounds are multifunctional reagents that provide for the separation and isolation of complex protein mixtures. Automated systems for performing the methods also are provided.

  提供了捕获化合物及其集合以及使用这些化合物进行生物分子分析的方法。特别地，提供了用于分析复杂蛋白质混合物（如蛋白质组）的集合、化合物和方法。这些化合物是多功能试剂，可用于分离和分离复杂的蛋白质混合物。还提供了执行这些方法的自动化系统。
• Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic delivery
  申请人：The Regents of the University of California

  公开号：US11021517B2

  公开（公告）日：2021-06-01

  The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.

  本发明提供了在手术过程中通过施用能与人神经元或人神经特异性结合的荧光标记肽来指导保存人神经元或人神经的方法。本发明进一步提供了人类神经元或神经靶向分子，包括特异性结合人类神经元或人类神经的荧光标记肽及其组合物。
• Capture compounds and methods for analyzing the proteome
  申请人：caprotec bioanalytics GmbH

  公开号：EP2259068B1

  公开（公告）日：2013-08-14
• Optimized Peptides for Targeting Human Nerves and Their Use in Image Guided Surgery, Diagnostics and Therapeutic Delivery
  申请人：The Regents of the University of California

  公开号：US20200239522A1

  公开（公告）日：2020-07-30

  The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
• US8569481B2
  申请人：——

  公开号：US8569481B2

  公开（公告）日：2013-10-29