(1R,5R)-1-Methoxy-6-oxa-bicyclo[3.2.0]heptan-7-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: (1R,5R)-1-Methoxy-6-oxa-bicyclo[3.2.0]heptan-7-one
• 英文别名: (1R,5R)-1-methoxy-6-oxabicyclo[3.2.0]heptan-7-one
• 化学式: C₇H₁₀O₃
• 分子量: 142.155
• InChiKey: ZKTPQGSHGVHSPV-IYSWYEEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  一氧化碳 、 Trifluoro-methanesulfonic acid 3,3-bis-benzyloxy-propyl ester 、 alkaline earth salt of/the/ methylsulfuric acid 生成 (1R,5R)-1-Methoxy-6-oxa-bicyclo[3.2.0]heptan-7-one
  参考文献：
  名称：

  Synthesis of .beta.-Lactones by the Photochemical Reactions of Chromium Alkoxycarbene Complexes with Aldehydes

  摘要：

  Photolysis of chromium alkoxycarbene complexes with aldehydes in the presence of Lewis acids produced beta-lactones in low yield. Incorporation of the aldehyde into either side chain of the carbene complex resulted in intramolecular processes which were considerably more efficient.

  DOI：

  10.1021/jo00096a047

文献信息

• Synthesis of .beta.-Lactones by the Photochemical Reactions of Chromium Alkoxycarbene Complexes with Aldehydes
  作者：Pierre-Jean Colson、Louis S. Hegedus

  DOI：10.1021/jo00096a047

  日期：1994.8

  Photolysis of chromium alkoxycarbene complexes with aldehydes in the presence of Lewis acids produced beta-lactones in low yield. Incorporation of the aldehyde into either side chain of the carbene complex resulted in intramolecular processes which were considerably more efficient.