N,N-diethyl-6,7-dimethoxy-3-(phenylsulfonyl)quinolin-4-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N,N-diethyl-6,7-dimethoxy-3-(phenylsulfonyl)quinolin-4-amine
• 英文别名: 3-(benzenesulfonyl)-N,N-diethyl-6,7-dimethoxyquinolin-4-amine
• 化学式: C₂₁H₂₄N₂O₄S
• 分子量: 400.5
• InChiKey: PMCQBGGTEOMSST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  77.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER
  申请人：Nir Uri

  公开号：US20110086861A1

  公开（公告）日：2011-04-14

  Provided is a pharmaceutical composition including as an active component a compound of formula (I): wherein X and (R 1 ) n are as defined, and a physiological acceptable carrier. Also provided is a method for treating cancer including administering to an individual in need of such treatment an effective amount of the presently described pharmaceutical composition.
• [EN] PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER<br/>[FR] COMPOSITIONS PHARMACEUTIQUES ET PROCÉDÉS POUR LE TRAITEMENT DU CANCER
  申请人：URIFER LTD

  公开号：WO2009019708A2

  公开（公告）日：2009-02-12

  The invention provides a pharmaceutical composition comprising as an active component a compound of formula (I); wherein X and (ROn are as defined, and a physiological acceptable carrier. The invention also provides a method for treating cancer comprising administering to an individual in need of such treatment an effective amount of a pharmaceutical composition of the invention. The invention further provides use of a compound of formula (I) for the preparation of a medicament for the treatment of cancer.