1-丁氧基-2-甲基丁烷 | 62238-03-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-丁氧基-2-甲基丁烷
• 英文名称: (2-methylbutyl)butyl ether
• 英文别名: 1-butoxy-2-methyl-butane；1-Butoxy-2-methyl-butan；1-Butyloxy-2-methyl-butan；1-Butoxy-2-methylbutane
• CAS: 62238-03-3
• 化学式: C₉H₂₀O
• 分子量: 144.257
• InChiKey: ZDKMWZZHCGSIRZ-UHFFFAOYSA-N

物化性质

• 沸点：
  73.4-74.3 °C(Press: 50 Torr)
• 密度：
  0.774 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2909199090

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 platinum(IV) oxide 、 乙醇 作用下， 生成 1-丁氧基-2-甲基丁烷
  参考文献：
  名称：

  Young; Roberts; Wax, Journal of the American Chemical Society, 1945, vol. 67, p. 842

  摘要：

  DOI：

文献信息

• NEUROMEDIN U DERIVATIVE
  申请人：Ohtaki Tetsuya

  公开号：US20100286035A1

  公开（公告）日：2010-11-11

  The objective of the present invention is to provide a new antifeedant. The other objective of the present invention is to provide a NMU derivative showing a high antifeedant activity even in common administration forms such as peripheral administration. A neuromedin U derivative wherein a methoxypolyethylene glycol is bound via a linker having a specific structure to a polypeptide which contains at least 8 amino acids of the C-terminus of an amino acid sequence of neuromedin U and which consists of the same or substantially the same amino acid sequence as the amino acid sequence of neuromedin U.

  本发明的目的是提供一种新的抗饲料剂。本发明的另一个目的是提供一种NMU衍生物，即使在常见的给药形式如周围给药中也表现出高抗饲料活性。一种神经介质U衍生物，其中通过具有特定结构的连接物将甲氧基聚乙二醇与包含神经介质U氨基酸序列C-末端至少8个氨基酸的多肽结合，该多肽由与神经介质U氨基酸序列相同或基本相同的氨基酸序列组成。
• COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES
  申请人：Laikhter Andrei

  公开号：US20090118482A1

  公开（公告）日：2009-05-07

  The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. The invention further provides compositions comprising labeled oligonucleotides and solid supports. The invention also provides kits comprising at least one composition of the present invention.

  本发明提供了一种新的寡核苷酸标记方法，包括但不限于猝灭剂、荧光染料、生物素、地高辛、肽和蛋白质等报告基团。此外，本发明还提供了一种检测寡核苷酸杂交的方法。本发明还提供了具有下列一般式的新的偶氮猝灭剂。本发明还提供了包含标记寡核苷酸和固体支持物的组合物。本发明还提供了至少包含一种本发明组合物的试剂盒。
• Transglutaminase Mediated Conjugation of Growth Hormone
  申请人：Dorwald Florencio Zaragoza

  公开号：US20100197573A1

  公开（公告）日：2010-08-05

  A method for PEGylating growth hormone, said method comprising reacting growth hormone with an amine comprising nucleophile which further comprises a first functional group in the presence og TGase to form a transaminated growth hormone, followed by a reaction of said transaminated growth hormone with a PEG which has been functionalised with a second functional group, wherein said first and second functional groups are selected so that they react to form a covalent bond.

  一种PEG化生长激素的方法，该方法包括在TGase的存在下，将生长激素与含有亲核基团的胺反应，所述亲核基团进一步包括第一功能基团，以形成转氨基化的生长激素，随后将所述转氨基化的生长激素与已经功能化了第二功能基团的PEG反应，其中所述第一和第二功能基团被选择为它们能够反应形成共价键。
• 1,2,4-TRIAZOLONE DERIVATIVE
  申请人：TAISHO PHARMACEUTICAL CO., LTD

  公开号：EP2623499A1

  公开（公告）日：2013-08-07

  The present invention provides a 1,2,4-triazolone derivative represented by Formula (1A) having an antagonistic activity on the arginine-vasopressin 1b receptor or a pharmaceutically acceptable salt thereof and provides a pharmaceutical composition comprising the compound or the salt as an active ingredient, in particular, a therapeutic or preventive agent exhibiting favorable pharmacokinetics in a disease such as mood disorder, anxiety disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal disease, drug addiction, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, head injury, inflammation, immune-related disease, or alopecia.

  本发明提供了一种由式（1A）表示的对精氨酸-血管加压素 1b 受体具有拮抗活性的 1，2，4-三唑酮衍生物或其药学上可接受的盐，并提供了一种包含该化合物或该盐作为活性成分的药物组合物，特别是、在诸如情绪障碍、焦虑症、精神分裂症、阿尔茨海默病、帕金森病、亨廷顿舞蹈症、饮食失调、高血压、胃肠道疾病、药物成瘾、癫痫、脑梗塞、脑缺血、脑水肿、头部损伤、炎症、免疫相关疾病或脱发等疾病中表现出良好药代动力学的治疗剂或预防剂。
• Regioselective reaction of functionally substituted mono-, di-, and triolefins with alkylmagnesium compounds, catalyzed by Cp2ZrCl2
  作者：U. M. Dzhemilev、O. S. Vostrikova、R. M. Sulmanov、A. G. Kukovinets、L. M. Khalilov

  DOI：10.1007/bf00948633

  日期：1984.9