1-氯-2-(氯甲基)-2-丁醇 | 100606-83-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-氯-2-(氯甲基)-2-丁醇
• 英文名称: 1-chloro-2-(chloromethyl)-2-butanol
• 英文别名: 1-chloro-2-(chloromethyl)butan-2-ol；1-chloro-2-chloromethyl-butan-2-ol；1.2¹-Dichlor-2-methyl-butanol-(2)；1-Chlor-2-chlormethyl-butan-2-ol；Bischlormethyl-aethyl-carbinol；1,1-bis(chloromethyl)-1-hydroxymethylethane
• CAS: 100606-83-5
• 化学式: C₅H₁₀Cl₂O
• mdl: MFCD19232279
• 分子量: 157.04
• InChiKey: UTHQFCOAGOLLSP-UHFFFAOYSA-N

物化性质

• 沸点：
  74 °C(Press: 16 Torr)
• 密度：
  1.2220 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-氯-2-(氯甲基)-2-丁醇 在 potassium hydroxide 作用下， 以 乙醚 为溶剂， 以80%的产率得到2-(氯甲基)-1,2-丁烯氧化物
  参考文献：
  名称：

  Synthesis and characterisation of thioether functionalised gallium and indium alkoxides

  摘要：

  巯醚在金属烷氧化物中的第一次配位被描述，并与含有巯醚的氨基醇酸衍生物进行了比较。

  DOI：

  10.1039/c5dt02777b
• 作为产物：
  描述：

  2-(氯甲基)-1-丁烯 、 氯脲 在 copper dichloride 硫酸 作用下， 生成 1-氯-2-(氯甲基)-2-丁醇
  参考文献：
  名称：

  Isagulyants,V.I.; Balashova,V.V., Journal of applied chemistry of the USSR, 1961, vol. 34, p. 405 - 410

  摘要：

  DOI：

文献信息

• Reactions of 2-Substituted Epichlorohydrins
  作者：Cihangir Tanyeli、Ayhan S. Demir、Idris M. Akhmedov、Emine Özgül、Canan G. Kandemir

  DOI：10.1080/00397919608004600

  日期：1996.8

  Abstract 2-Substituted epichlorohydrins have been synthesized by starting with 1,2-dichloro acetone and various alkyl and aryl halides via dichlorohydrins followed by cyclization. The reactive 2-substituted epichlorohydrins were subjected to nucleophilic attacking of azide and cyanide ions to afford corresponding β-azido alcohols and α,β-unsaturated nitriles.

  摘要 以 1,2-二氯丙酮和各种烷基和芳基卤化物为原料，通过二氯醇，然后环化，合成了 2-取代的环氧氯丙烷。反应性的 2-取代表氯醇受到叠氮化物和氰化物离子的亲核攻击，得到相应的 β-叠氮醇和 α,β-不饱和腈。
• Placing Aboriginal and Torres Strait Islander mortality in an international context
  作者：Yin Paradies、Joan Cunningham

  DOI：10.1111/j.1467-842x.2002.tb00264.x

  日期：2002.2

  Objective: To assess whether the patterns of mortality observed among Indigenous Australians were seen in other countries or sub-populations. Previous reports have indicated that the life expectancy of Indigenous Australians compares unfavourably with that of Indigenous groups in other developed countries, and is similar to that in some developing countries. However, in contrast to many developing countries, low life expectancy of Indigenous Australians is the result of relatively high and early adult mortality, rather than high infant mortality.Methods: Using routinely available administrative data on age-specific mortality and estimated life expectancy at birth, we compared data for Indigenous Australians (from the Northern Territory, Western Australia and South Australia combined) with corresponding data for 200 countries world-wide, as well as for several population groups of interest, including African Americans, Native Americans, Canadian Natives and New Zealand Maori. Results: Patterns of mortality among Indigenous Australians were markedly different to those of most other populations with available data, with the exception of the Russian Republic. The age-specific mortality rates for Russian males in 1990-95 were almost identical to those of Indigenous males in 1995-97. The similarities among females were less pronounced, but stronger than for any other country.Conclusion and implications: The dramatic fall in Russian life expectancy has been studied extensively and several important social and contextual factors have been identified. These factors are also relevant for the Indigenous population, and this may help to explain the similar mortality patterns of the two groups.
• DE168941
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  公开（公告）日：——
• DE173610
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• US5886199A
  申请人：——

  公开号：US5886199A

  公开（公告）日：1999-03-23