1-氯-3-(3-硝基苯氧基)苯 | 37983-99-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-氯-3-(3-硝基苯氧基)苯
• 英文名称: 1-chloro-3-(3-nitrophenoxy)benzene
• 英文别名: (3-chloro-phenyl)-(3-nitro-phenyl)-ether；(3-Chlor-phenyl)-(3-nitro-phenyl)-aether；3-(3-chlorophenoxy)nitrobenzene；3-Chlor-3'-nitro-diphenylaether；1-(3-chlorophenoxy)-3-nitrobenzene
• CAS: 37983-99-6
• 化学式: C₁₂H₈ClNO₃
• 分子量: 249.653
• InChiKey: HNDPSMNFOPNENB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-氯-3-(3-硝基苯氧基)苯 在 一水合肼 作用下， 生成 3-(3-氯-苯氧基)-苯胺
  参考文献：
  名称：

  Ikawa, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1959, vol. 79, p. 273,275

  摘要：

  DOI：
• 作为产物：
  描述：

  3-氯苯酚 、 间氟硝基苯 以 二甲基亚砜 为溶剂， 生成 1-氯-3-(3-硝基苯氧基)苯
  参考文献：
  名称：

  Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation

  摘要：

  具有以下公式的化合物： 其中R3和M的定义如本文所述，以及与此相关的过程。

  公开号：

  US06355660B1

文献信息

• Fungicidal 2-pyridyl alkyl amides and their compositions, methods of use and preparation
  申请人：Ricks Michael J.

  公开号：US06927225B2

  公开（公告）日：2005-08-09

  The present invention relates to compounds of Formula I: wherein: represents a 6-membered heterocyclic aromatic ring in which X 1 is N, and X 2 , X 3 and X 4 are CR″; wherein R″ is independently H, halogen, cyano, hydroxy, C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, cyclopropyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, C 1 -C 3 alkylthio, aryl, C 1 -C 3 NHC(O)alkyl, NHC(O)H, C 1 -C 3 haloalkylthio, C 2 -C 4 alkenyl, C 2 -C 4 haloalkenyl, C 2 -C 4 alkynyl, C 2 -C 4 haloalkynyl or nitro wherein adjacent R″ substituents may form a ring; b) Z is O, S or NOR z in which R z is H or C 1 -C 3 alkyl; and c) A represents (i) C 2 -C 14 alkenyl, or C 2 -C 14 alkynyl, all of which may be branched or unbranched, unsubstituted or substituted with halogen, hydroxy, nitro, aroyl, aryloxy, C 1 -C 8 acyloxy, C 1 -C 6 alkylthio, arylthio, aryl, heteroaryl, heteroarylthio, heteroaryloxy, C 1 -C 6 acyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or C 1 -C 6 haloalkoxy, and (ii) C 3 -C 14 cycloalkyl, containing 0 heteroatoms and 0-2 unsaturations, substituted with aryloxy, heteroaryloxy, C 1 -C 6 alkylthio, arylthio, heteroarylthia, C 1 -C 6 alkoxy, or C 1 -C 6 haloalkoxy; which are useful as antifungal agents, particularly for plants.

  本发明涉及式I的化合物: 其中: 表示一个6元杂环芳香环，其中X1为N，而X2、X3和X4为CR″; 其中R″独立地为H、卤素、氰基、羟基、C1-C3烷基、C1-C3卤代烷基、环丙基、C1-C3烷氧基、C1-C3卤代烷氧基、C1-C3烷硫基、芳基、C1-C3NHC（O）烷基、NHC（O）H、C1-C3卤代烷硫基、C2-C4烯基、C2-C4卤代烯基、C2-C4炔基、C2-C4卤代炔基或硝基，其中相邻的R″取代基可以形成环; b) Z为O、S或NORzin，其中Rz为H或C1-C3烷基; 和 c) A表示(i) C2-C14烯基或C2-C14炔基，全部可以是支链的或非支链的，未取代或取代为卤素、羟基、硝基、芳酰基、芳氧基、C1-C8酰氧基、C1-C6烷基硫基、芳基硫基、芳基、杂芳基、杂芳基硫基、杂芳基氧基、C1-C6酰基、C1-C6卤代烷基、C1-C6烷氧基或C1-C6卤代烷氧基; 和 (ii) C3-C14环烷基，不含杂原子和0-2个不饱和度，取代为芳氧基、杂芳氧基、C1-C6烷基硫基、芳基硫基、杂芳硫基、C1-C6烷氧基或C1-C6卤代烷氧基; 这些化合物可用作抗真菌剂，特别是用于植物。
• Fungicidal mono-, bi-, and tri-cycloheteroalkyl amides and their compositions, methods of use and preparation
  申请人：Dow AgroSciences LLC

  公开号：US07034035B2

  公开（公告）日：2006-04-25

  The present invention relates to compounds of Formula I: wherein: a)  represents a 6-membered heterocyclic aromatic ring in which X1 is N and X2, X3 and X4 are each independently CR″; R″ is independently H, halogen, cyano, hydroxy, C1-C3 alkyl, C1-C3 haloalkyl, cyclopropyl, C1-C3 alkoxy, C1-C3 haloalkoxy, C1-C3 alkylthio, aryl, C1-C3 NHC(O)alkyl, NHC(O)H, C1-C3 haloalkylthio, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl or nitro wherein adjacent R″ substituents may form a ring; b) Z is O, S or NORZ in which RZ is H or C1-C3 alkyl; and c) A represents (i) C3-C14 cycloalkyl, containing 1 or 3 heteroatoms and 0-2 unsaturations, which may be unsubstituted or substituted with halogen, hydroxy, C1-C6 alkyl, C1-C6 haloalkyl, cyano, nitro, aroyl, aryloxy, heteroaryloxy, C1-C6 alkylthio, arylthio, heteroarylthio, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C8 acyloxy, aryl, heteroaryl, C1-C6 acyl, C1-C6 carboalkoxy or amido unsubstituted or substituted with one or two C1 -C6 alkyl groups, or (ii) C6-C14 bi- or tricyclic ring system, containing 1-3 heteroatoms and 0-2 unsaturations, which may be unsubstituted or substituted with halogen, hydroxy, C1-C6 alkyl, C1-C6 haloalkyl, cyano, nitro, aroyl, aryloxy, heteroaryloxy, C1-C6 alkylthio, arylthio, heteroarylthio, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C8 acyloxy, aryl, heteroaryl, C1-C6 acyl, C1-C6 carboalkoxy or amido unsubstituted or substituted with one or two C1-C6 alkyl groups; which are useful as antifungal agents, particularly for plants.

  本发明涉及公式I的化合物：其中：a) 表示一个6元杂环芳香环，其中X1为N，X2，X3和X4分别独立为CR″；R″独立为H，卤素，氰基，羟基，C1-C3烷基，C1-C3卤代烷基，环丙基，C1-C3烷氧基，C1-C3卤代烷氧基，C1-C3烷基硫基，芳基，C1-C3NHC（O）烷基，NHC（O）H，C1-C3卤代烷基硫基，C2-C4烯基，C2-C4卤代烯基，C2-C4炔基，C2-C4卤代炔基或硝基，其中相邻的R″取代基可以形成环；b) Z为O，S或NORZ，其中RZ为H或C1-C3烷基；c) A表示（i）C3-C14环烷基，含有1或3个杂原子和0-2个不饱和度，可能未取代或取代为卤素，羟基，C1-C6烷基，C1-C6卤代烷基，氰基，硝基，芳酰基，芳氧基，杂芳氧基，C1-C6烷硫基，芳硫基，杂芳硫基，C1-C6烷氧基，C1-C6卤代烷氧基，C1-C8酰氧基，芳基，杂芳基，C1-C6酰基，C1-C6羧酸烷酯或未取代或取代一个或两个C1-C6烷基的酰胺；或（ii）C6-C14双环或三环环系统，含有1-3个杂原子和0-2个不饱和度，可能未取代或取代为卤素，羟基，C1-C6烷基，C1-C6卤代烷基，氰基，硝基，芳酰基，芳氧基，杂芳氧基，C1-C6烷硫基，芳硫基，杂芳硫基，C1-C6烷氧基，C1-C6卤代烷氧基，C1-C8酰氧基，芳基，杂芳基，C1-C6酰基，C1-C6羧酸烷酯或未取代或取代一个或两个C1-C6烷基的酰胺；它们可用作抗真菌剂，特别是用于植物。
• Fungicidal heterocyclic aromatic amides, their compositions and methods of use
  申请人：Dow AgroSciences LLC

  公开号：EP1493733A2

  公开（公告）日：2005-01-05

  The present invention relates to the field of fungicidal compositions and methods. More particularly, the present invention concerns novel fungicidal heterocyclic aromatic amides of following formula I: wherein: represents a 5 membered heterocyclic aromatic ring, and methods involving application of fungicidally effective amounts of such compounds to the locus of a plant pathogen. The present invention also concerns methods useful in the preparation of heterocyclic aromatic amides and their fungicidal compositions.

  本发明涉及杀菌组合物和方法领域。更具体地说，本发明涉及下式 I 的新型杀菌杂环芳香酰胺： 其中 代表 5 个成员的杂环芳香环，以及将杀真菌有效量的此类化合物施用到植物病原体位点的方法。本发明还涉及用于制备杂环芳香酰胺及其杀菌组合物的方法。
• DE2118190
  申请人：——

  公开号：——

  公开（公告）日：——
• Studies on selective nucleophilic substitution reactions of [(cyclopentadienyl)(1,3-dichlorobenzene)M]+ PF6- complexes (M = iron, ruthenium)
  作者：Anthony J. Pearson、Jewn G. Park、Ping Y. Zhu

  DOI：10.1021/jo00039a015

  日期：1992.6

  Reactions of [cyclopentadienyl)(1,3-dichlorobenzene)M]+PF6- complexes (M = Fe, Ru) with phenoxide nucleophiles were found to proceed with excellent selectivity under mild conditions to give products of monosubstitution. Using aminophenoxides, a preference for O-arylation was observed, while amino alcohols such as prolinol react selectively on nitrogen. Methodology for sequential selective displacement of both chlorides by different nucleophiles is reported.