Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I)
wherein the substituents are as defined herein, which are useful as therapeutic agents.
Arylazobenzimidazoles: versatile visible-light photoswitches with tuneable <i>Z</i>-isomer stability
作者:Sophie A. M. Steinmüller、Magdalena Odaybat、Giulia Galli、Davia Prischich、Matthew J. Fuchter、Michael Decker
DOI:10.1039/d3sc05246j
日期:——
Arylazobenzimidazoles are photoswitchable privileged structures in medicinal chemistry. Experimental and theoretical studies identified compounds with visible light near-quantitative bidirectional photoswitching and highly tunable Z-isomer stability.
芳基偶氮苯并咪唑是药物化学中的光开关特权结构。实验和理论研究发现了具有可见光近定量双向光开关和高度可调 Z 异构体稳定性的化合物。