1-羟基环己烷-1,2-二羧酸 | 155915-30-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-羟基环己烷-1,2-二羧酸
• 英文名称: 1-Hydroxy-1,2-cyclohexanedicarboxylic acid
• 英文别名: 1-Hydroxycyclohexane-1,2-dicarboxylic acid
• CAS: 155915-30-3
• 化学式: C₈H₁₂O₅
• 分子量: 188.18
• InChiKey: SSBQOSIEGFXXEQ-UHFFFAOYSA-N

物化性质

• 熔点：
  178 °C
• 沸点：
  446.8±45.0 °C(Predicted)
• 密度：
  1.489±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  94.8
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-羟基环己烷-1,2-二羧酸 170.0 ℃ 、2.67 kPa 条件下， 生成 3,4,5,6-四氢苯酐
  参考文献：
  名称：

  Recurrent gallstone ileus: a case report

  摘要：

  Gallstone ileus is a rare complication of recurrent gallstone cholecystitis and usually occurs in elderly female patients. Recurrent gallstone ileus occurs in 5% of patients with a previous episode of gallstone ileus and is associated with a mortality of 20%. We present a 52-year-old female with recurrent gallstone ileus 1 year after her initial episode.

  DOI：

  10.1007/s10140-002-0203-1
• 作为产物：
  描述：

  2-环己酮甲酸乙酯 在 盐酸 、 sodium cyanide 作用下， 生成 1-羟基环己烷-1,2-二羧酸
  参考文献：
  名称：

  Recurrent gallstone ileus: a case report

  摘要：

  Gallstone ileus is a rare complication of recurrent gallstone cholecystitis and usually occurs in elderly female patients. Recurrent gallstone ileus occurs in 5% of patients with a previous episode of gallstone ileus and is associated with a mortality of 20%. We present a 52-year-old female with recurrent gallstone ileus 1 year after her initial episode.

  DOI：

  10.1007/s10140-002-0203-1

文献信息

• Hexahydrophthalate based compound and process for producing the same
  申请人：Shieh Sung-Yueh

  公开号：US20090281349A1

  公开（公告）日：2009-11-12

  A hexahydrophthalate based compound is adapted to use as a plasticizer that contains no phthalic acid and benzoic acid, possess physical properties superior to DEHA and DINA in transparency and adhesion and is friendly to organisms and the environment; and a process for producing the hexahydrophthalate based compound includes esterifying hexahydrophthalic anhydride, a diol, and a catalyst for decarboxylation to get hexahydrophthalic alcohol, and adding a monoacid into the hexahydrophthalic alcohol for further esterification, thereby obtaining the hexahydrophthalate based compound.

  一种基于六氢邻苯二甲酸酯的化合物被改进用作增塑剂，不含邻苯二甲酸和苯甲酸，具有优于DEHA和DINA的透明度和粘附性能，并对生物体和环境友好；生产基于六氢邻苯二甲酸酯的化合物的方法包括酯化六氢邻苯二甲酸酐、二元醇和脱羧催化剂以获得六氢邻苯二甲醇，并将一种单酸加入六氢邻苯二甲醇进行进一步酯化，从而获得基于六氢邻苯二甲酸酯的化合物。
• US8017799B2
  申请人：——

  公开号：US8017799B2

  公开（公告）日：2011-09-13