1H-咪唑,2-乙基-1,5-二甲基-(9CI) | 112725-81-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 中文名称: 1H-咪唑,2-乙基-1,5-二甲基-(9CI)
• 英文名称: 2-Ethyl-1,5-dimethyl-1H-imidazole
• 英文别名: 2-ethyl-1,5-dimethylimidazole
• CAS: 112725-81-2
• 化学式: C₇H₁₂N₂
• 分子量: 124.186
• InChiKey: KACBWSJPLBIMGN-UHFFFAOYSA-N

物化性质

• 沸点：
  233.1±9.0 °C(Predicted)
• 密度：
  0.96±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-乙基-4-甲基咪唑 、 碘甲烷 在 18-冠醚-6 、 potassium tert-butylate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 12.0h， 生成 1H-咪唑,2-乙基-1,5-二甲基-(9CI) 、 1,4-dimethyl-2-ethylimidazole
  参考文献：
  名称：

  Photo-, Solvent-, and Ion-Controlled Multichromism of Imidazolium-Substituted Diarylethenes

  摘要：

  AbstractSeeing red: Imidazolium‐substituted diarylethenes show solvent‐ and ion‐controlled chromisms in addition to reversible photochromic reactions. The shift of equilibrium between two closed‐ring isomers with different π‐conjugation length by interaction with nucleophilic species is responsible for the multichromic property (see scheme).magnified imageCationic diarylethenes with an imidazolium ring are synthesized for the first time. The imidazolium cationic moiety is connected directly to the ethene unit as one of the aryl units that take part in the photoinduced pericyclization reaction. The imidazolium‐substituted diarylethenes undergo reversible photochromic reactions in a variety of organic media, including ionic liquids, even though they have a delocalized cationic charge in one of the five‐membered aromatic rings. The closed‐ring isomer shows solvatochromism depending on the solvent donor numbers. Addition of some tetraalkylammonium salts, such as tetrabutyl ammonium nitrate, into the colored organic solution of diarylethene also causes a color change, indicating its ionochromic property. These solvato‐ and ionochromic properties are considered in connection with the shift of chemical equilibrium between the closed‐ring isomers, one with an extended π‐conjugation system and one with limited π‐conjugation due to the strong interaction with solvent molecules and anions with high donor number.

  DOI：

  10.1002/chem.200801192

文献信息

• [EN] HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES EN TANT QU'ANTAGONISTES DE L'ADÉNOSINE
  申请人：NUVATION BIO INC

  公开号：WO2020150677A1

  公开（公告）日：2020-07-23

  Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.

  提供了氨基吡嗪化合物作为腺苷受体的调节剂。这些化合物可能作为治疗经由G蛋白偶联受体信号通路介导的疾病的治疗剂，并且可能在肿瘤学中发挥特定作用。
• Method for producing haloalkanes from alcohols
  申请人：Stegmann Viet

  公开号：US20070055084A1

  公开（公告）日：2007-03-08

  The invention relates to a process for preparing haloalkanes by reaction of alcohol with hydrogen halide, wherein the reaction of the alcohol with the hydrogen halide occurs in the presence of an ionic liquid at a temperature which is above 100° C. for at least part of the time and, at least at the time of the commencement of the reaction, the water content is not more than 25 mol % based on the amount of liquid, where the ionic liquid is not octyltrimethylammonium chloride.

  该发明涉及一种通过醇与氢卤化物反应制备卤代烷的方法，其中醇与氢卤化物的反应在存在离子液体的条件下进行，反应温度在100°C以上至少一部分时间，并且至少在反应开始时，水含量不超过液体总量的25摩尔％，其中所述离子液体不是辛基三甲基铵氯化物。
• OXOPIPERAZINE DERIVATIVES
  申请人：Inthera Bioscience AG

  公开号：US20190185449A1

  公开（公告）日：2019-06-20

  The present invention relates to novel compounds of formula (I) or formula (Ia) pharmaceutically-acceptable salts, hydrates, solvates, or stereoisomers thereof, and pharmaceutical compositions of these compounds which are useful for preventive and therapeutic use in human and veterinary medicine.

  本发明涉及化学式（I）或化学式（Ia）的新化合物及其药用盐、水合物、溶剂合物或立体异构体，以及这些化合物的药物组合物，可用于人类和兽医药物的预防和治疗。
• [DE] NITRILHYDRIERUNG IN GEGENWART IONISCHER FLÜSSIGKEITEN AN HETEROGENEN KATALYSATOREN<br/>[EN] NITRILE HYDROGENATION ON HETEROGENEOUS CATALYSTS IN THE PRESENCE OF IONIC LIQUIDS<br/>[FR] HYDROGENATION DE NITRILE EN PRESENCE DE LIQUIDES IONIQUES SUR DES CATALYSEURS HETEROGENES
  申请人：BASF AG

  公开号：WO2005061429A1

  公开（公告）日：2005-07-07

  Beschrieben wird ein Verfahren zur Hydrierung von in organischen Verbindungen enthaltenen Nitrilfunktionen an mindestens einem heterogenen Katalysator, wobei die Hydrierung in Gegenwart einer ionischen Flüssigkeit durchgeführt wird.

  描述了一种在至少一个异质催化剂存在的有机化合物中的腈基团进行加氢的方法，其中在离子液体存在下进行加氢。
• PROCESS FOR PRODUCING 1-CHLORO-3,3,3-TRIFLUOROPROPENE IN AN IONIC LIQUID
  申请人：Honeywell International Inc.

  公开号：US20150105596A1

  公开（公告）日：2015-04-16

  This invention relates to methods and systems for producing hydrochlorofluoro-olefins, particularly 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd) by the fluorination of a starting material selected from the group consisting of 1,1,1,3,3-pentachloropropane (HCC-240fa), 1,1,3,3-tetrachloropropene, and 1,1,1,3-tetrachloropropene, alone or in combination, in an ionic liquid.

  本发明涉及一种生产氯氟烯烃的方法和系统，特别是通过在离子液体中将选自1,1,1,3,3-五氯丙烷（HCC-240fa）、1,1,3,3-四氯丙烯和1,1,1,3-四氯丙烯的起始物单独或组合进行氟化而生产1-氯-3,3,3-三氟丙烯（HCFO-1233zd）。