2,3,4,5,5,5-六氟-2,4-二(三氟甲基)-1-戊醇 | 25065-50-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 中文名称: 2,3,4,5,5,5-六氟-2,4-二(三氟甲基)-1-戊醇
• 中文别名: 2,3,4,5,5,5-六氟-2,4-双(三氟甲基)-1-戊醇
• 英文名称: 1,1,3-trihydroperfluoro-2,4-dimethylpentan-1-ol
• 英文别名: (CF₃)₂CF-CFH-(CF₃)CF-CH₂OH；2,3,4,5,5,5-hexafluoro-2,4-bis-trifluoromethyl-pentan-1-ol；2,3,4,5,5,5-Hexafluoro-2,4-bis(trifluoromethyl)pentan-1-ol
• CAS: 25065-50-3
• 化学式: C₇H₄F₁₂O
• 分子量: 332.089
• InChiKey: PCGUNVYNJIFBQT-UHFFFAOYSA-N

物化性质

• 沸点：
  139.6±35.0 °C(Predicted)
• 密度：
  1.6 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  13

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36/37/39
• 危险类别码：
  R36/37/38
• 海关编码：
  2905590090

反应信息

• 作为反应物：
  描述：

  环氧乙烷 、 2,3,4,5,5,5-六氟-2,4-二(三氟甲基)-1-戊醇 在 三氟化硼乙醚 作用下， 以 乙醚 为溶剂， 反应 0.17h， 生成 (CF₃)₂CF-CFH-(CF₃)CF-CH₂O-CH₂CH₂OH
  参考文献：
  名称：

  FLUOROSURFACTANTS HAVING IMPROVED BIODEGRADABILITY

  摘要：

  为了解决全氟表面活性剂生物降解性不足的问题，本发明提供了由具有—CHR、—CHRf、—CHF和/或—CH2基团的烯烃衍生的可生物降解的氟表面活性剂，其中R为烷基，Rf为全氟或氟烷基。最好，—CHR、—CHRf、—CHF和/或—CH2基团包含在部分氟化的烯烃中。

  公开号：

  US20150065746A1
• 作为产物：
  描述：

  甲醇 、 perfluoro-4-methyl-2-pentene 生成 2,3,4,5,5,5-六氟-2,4-二(三氟甲基)-1-戊醇
  参考文献：
  名称：

  ESR spectra of spin-adducts of hydroxyalkyl radicals with perfluoro-4-methyl-2-pentene

  摘要：

  A study was carried out on the ESR spectra of the spin-adducts of hydroxyalkyl radicals with perfluoro-4-methyl-2-pentene (I) formed upon the photolysis of alcoholic solutions of this perfluoroolefin. The stable conformational positions of the substituents in the spin-adducts depend on the structure of the hydroxyalkyl radicals. The spin-adducts are annihilated as a consequence of hydrogen atom abstraction as indicated in a preparative experiment.

  DOI：

  10.1007/bf00958012

文献信息

• MANUFACTURE OF FLUORINATED ALCOHOLS
  申请人：Der Puy Van Michael

  公开号：US20050256331A1

  公开（公告）日：2005-11-17

  Present invention relates to a process for the manufacture of fluorinated alcohols as well as borates which are employed in the manufacture of the fluorinated alcohols. Fluorinated alcohols of the formulae HOCHRCF(CF 3 )CHFCF(CF 3 ) 2 and HOCHRCF(CF(CF 3 ) 2 )CHFCF 3 , HOCHRCF(CF 2 CF 3 )CH(CF 3 ) 2 and HOCHRC(CF 3 ) 2 CHFCF 2 CF 3 are made by heating a mixture of a borate of the formula (RCH 2 O) 3 B, wherein R═H or a C 1 to C 7 alkyl group, with perfluoro-4-methyl-2-pentene or perfluoro-2-methyl-2-pentene and a free-radical initiator to form a mixture of borates, optionally separating the mixture of borates from any reactants, solvents, and by-products; hydrolyzing the mixture of borates to form a hydrolysis product mixture; and separating the alcohols from the hydrolysis product mixture.

  本发明涉及一种用于制造氟化醇和硼酸盐的工艺，该硼酸盐用于制造氟化醇。通过加热公式为HOCHRCF(CF3)CHFCF(CF3)2和HOCHRCF(CF(CF3)2)CHFCF3、HOCHRCF(CF2CF3)CH(CF3)2和HOCHRC(CF3)2CHFCF2CF3的氟化醇的混合物与公式为(RCH2O)3B的硼酸盐（其中R=H或C1至C7烷基）以及全氟-4-甲基-2-戊烯或全氟-2-甲基-2-戊烯和自由基引发剂反应，形成硼酸盐的混合物，可选择地将硼酸盐的混合物与任何反应物、溶剂和副产物分离；水解硼酸盐的混合物以形成水解产物混合物；并从水解产物混合物中分离出醇。
• Radiochemical addition of alcohols to perfluoro-2-alkenes
  作者：M.A. Kurykin、L.S. German、L.I. Kartasheva、A.K. Pikaev

  DOI：10.1016/0022-1139(96)03405-7

  日期：1996.4

  Radical addition of aliphatic alcohols to internal perfluorinated olefins has been studied. The process occurs non-stereoselectively to give equimolar mixtures of diastereoisomers in all cases.

  已经研究了向内部全氟化烯烃中自由基加成脂肪族醇的方法。在所有情况下，该过程均非立体选择性地生成非对映异构体的等摩尔混合物。
• Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foams stabilizers
  申请人：Boggs Janet

  公开号：US20070149437A1

  公开（公告）日：2007-06-28

  Production processes and systems are provided that include reacting halogenated compounds, dehalogenating compounds, reacting alcohols, reacting olefins and a saturated compounds, reacting reactants having at least two —CF 3 groups with reactants having cyclic groups. RF compositions such as R F -intermediates, R F -surfactants, R F -monomers, R F- monomer units, R F -metal complexes, R F -phosphate esters, R F -glycols, R F urethanes, and/or R F -foam stabilizers. The R F portion can include at least two —CF 3 groups, at least three —CF 3 groups, and/or at least two —CF 3 groups and at least two —CH 2 — groups. Detergents, emulsifiers, paints, adhesives, inks, wetting agents, foamers, and defoamers including the R F -surfactant composition are provided. Acrylics, resins, and polymers are provided that include a R F -monomer unit Compositions are provided that include a substrate having a R F -composition thereover. Aqueous Film Forming Foam (“AFFF”) formulations are provided that can include R F -surfactants and/or R F -foam stabilizers are provided.

  提供生产过程和系统，包括反应卤代化合物，脱卤化合物，反应醇，反应烯烃和饱和化合物，将至少含有两个—CF3基团的反应物与具有环状基团的反应物反应。提供RF组分，例如RF中间体，RF表面活性剂，RF单体，RF单体单元，RF金属络合物，RF磷酸酯，RF乙二醇，RF聚氨酯和/或RF泡沫稳定剂。RF部分可以包括至少两个—CF3基团，至少三个—CF3基团，和/或至少两个—CF3基团和至少两个—CH2—基团。提供包括RF表面活性剂组分的清洁剂，乳化剂，油漆，粘合剂，油墨，润湿剂，发泡剂和消泡剂。提供包括RF单体单元的丙烯酸，树脂和聚合物。提供包括具有RF组分的基底的组合物。提供包括RF表面活性剂和/或RF泡沫稳定剂的水性成膜泡沫（“AFFF”）配方。
• Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams and foam stabilizers
  申请人：Boggs Janet

  公开号：US20070161537A1

  公开（公告）日：2007-07-12

  Production processes and systems are provided that include reacting halogenated compounds, dehalogenating compounds, reacting alcohols, reacting olefins and a saturated compounds, reacting reactants having at least two —CF 3 groups with reactants having cyclic groups. R F -compositions such as R F -intermediates, R F -surfactants, R F monomers, R F -monomer units, R F -metal complexes, R F -phosphate esters, R F -glycols, R F -urethanes, and/or R F -foam stabilizers. The R F portion can include at least two CF 3 groups, at least three —CF 3 groups, and/or at least two —CF 3 groups and at least two —CH 2 — groups. Detergents, emulsifiers, paints, adhesives, inks, wetting agents, foamers, and defoamers including the R F -surfactant composition are provided. Acrylics, resins, and polymers are provided that include a R F -monomer unit. Compositions are provided that include a substrate having a R F -composition thereover. Aqueous Film Forming Foam (“AFFF”) formulations are provided that can include R F surfactants and/or R F -foam stabilizers are provided.

  提供了生产过程和系统，其中包括反应卤代化合物，去卤化化合物，反应醇，反应烯烃和饱和化合物，反应至少有两个—CF3基团的反应物与具有环状基团的反应物反应。提供了RF组分，例如RF中间体，RF表面活性剂，RF单体，RF单体单元，RF金属配合物，RF磷酸酯，RF乙二醇，RF聚氨酯和/或RF泡沫稳定剂。RF部分可以包括至少两个CF3基团，至少三个—CF3基团，以及至少两个—CF3基团和至少两个—CH2—基团。提供了包括RF表面活性剂组分的洗涤剂、乳化剂、油漆、粘合剂、油墨、润湿剂、起泡剂和消泡剂。提供了包括RF单体单元的丙烯酸、树脂和聚合物。提供了包括具有RF组分的基底的组合物。提供了可以包括RF表面活性剂和/或RF泡沫稳定剂的水性成膜泡沫（“AFFF”）配方。
• Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Foams, and Foam Stabilizers
  申请人：Boggs Janet

  公开号：US20070282115A1

  公开（公告）日：2007-12-06

  Production processes and systems are provided that include reacting halogenated compounds, dehalogenating compounds, reacting alcohols, reacting olefins and a saturated compounds, reacting reactants having at least two —CF 3 groups with reactants having cyclic groups. R F -compositions such as R F -intermediates, R F -surfactants, R F -monomers, R F -monomer units, R F -metal complexes, R F -phosphate esters, R F -glycols, R F -urethanes, and/or R F -foam stabilizers. The R F portion can include at least two —CF 3 groups, at least three —CF 3 groups, and/or at least two —CF 3 groups and at least two —CH 2 — groups. Detergents, emulsifiers, paints, adhesives, inks, wetting agents, foamers, and defoamers including the R F -surfactant composition are provided. Acrylics, resins, and polymers are provided that include a R F -monomer unit. Compositions are provided that include a substrate having a R F -composition thereover. Aqueous Film Forming Foam (“AFFF”) formulations are provided that can include R F -surfactants and/or R F -foam stabilizers are provided.

  提供了包括反应卤代化合物、脱卤化合物、反应醇、反应烯烃和饱和化合物、反应至少具有两个-CF3基团的反应物与具有环状基团的反应物的生产过程和系统。提供了RF组分，例如RF中间体、RF表面活性剂、RF单体、RF单体单元、RF金属配合物、RF磷酸酯、RF乙二醇、RF聚氨酯和/或RF泡沫稳定剂。RF部分可以包括至少两个-CF3基团、至少三个-CF3基团，以及至少两个-CF3基团和至少两个-CH2-基团。提供了包括RF表面活性剂组分的洗涤剂、乳化剂、油漆、粘合剂、油墨、润湿剂、起泡剂和消泡剂。提供了包括RF单体单元的丙烯酸、树脂和聚合物。提供了包括RF组分覆盖在基底上的组合物。提供了可以包括RF表面活性剂和/或RF泡沫稳定剂的水性成膜泡沫（“AFFF”）配方。